Pharmacokinetics, surrogate efficacy and safety evaluations of a new human plasma-derived fibrinogen concentrate (FIB Grifols) in adult patients with congenital afibrinogenemia.
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DOI: 10.1016/j.thromres.2020.12.026
Abstract: BACKGROUND AND AIMS Congenital afibrinogenemia is a rare coagulation disorder resulting from a deficiency in fibrinogen. This study assessed the pharmacokinetics, surrogate efficacy and safety of FIB Grifols, a new human plasma-derived fibrinogen concentrate, to… read more here.
Keywords: plasma; congenital afibrinogenemia; surrogate efficacy; efficacy ... See more keywords