Photoinduced Amyloid Fibril Degradation for Controlled Cell Patterning.
Sign Up to like & getrecommendations! Published in 2022 at "Macromolecular bioscience"
DOI: 10.1002/mabi.202200294
Abstract: Amyloid-like fibrils are a special class of self-assembling peptides that have emerged as a promising nanomaterial with rich bioactivity for applications such as cell adhesion and growth. Unlike the extracellular matrix, the intrinsically stable amyloid-like… read more here.
Keywords: cell; cell patterning; fibril; amyloid like ... See more keywords
Modeling the effect of collagen fibril alignment on ligament mechanical behavior
Sign Up to like & getrecommendations! Published in 2018 at "Biomechanics and Modeling in Mechanobiology"
DOI: 10.1007/s10237-017-0977-4
Abstract: Ligament mechanical behavior is primarily regulated by fibrous networks of type I collagen. Although these fibrous networks are typically highly aligned, healthy and injured ligament can also exhibit disorganized collagen architecture. The objective of this… read more here.
Keywords: collagen; ligament; mechanical behavior; collagen fibril ... See more keywords
Influence of fibril aspect ratio, chemical functionality, and volume fraction on the mechanical properties of cellulose nanofibril materials
Sign Up to like & getrecommendations! Published in 2024 at "Cellulose"
DOI: 10.1007/s10570-024-06084-4
Abstract: Nanocellulose has emerged as a widely utilized building block in nanostructured materials due to its availability, sustainability, large surface area, and high stiffness and aspect ratio. The wet or dry elastoplastic properties of these materials… read more here.
Keywords: ratio; chemical functionality; fibril; aspect ratio ... See more keywords
The effect of fixed charge density and cartilage swelling on mechanics of knee joint cartilage during simulated gait.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of biomechanics"
DOI: 10.1016/j.jbiomech.2017.06.041
Abstract: The effect of swelling of articular cartilage, caused by the fixed charge density (FCD) of proteoglycans, has not been demonstrated on knee joint mechanics during simulated walking before. In this study, the influence of the… read more here.
Keywords: mechanics; knee joint; effect; model ... See more keywords
Self-assembly characterization of tilapia skin collagen in simulated body fluid with different salt concentrations
Sign Up to like & getrecommendations! Published in 2021 at "Process Biochemistry"
DOI: 10.1016/j.procbio.2021.06.013
Abstract: Abstract The characteristics and self-assembly properties of acid soluble collagen (ASC) from tilapia skin in simulated body fluid (SBF) with different NaCl concentrations were investigated. When the concentration of NaCl was 65 mM, the lag… read more here.
Keywords: fibril; tilapia skin; nacl concentration; collagen ... See more keywords
Ultraeffective Inhibition of Amyloid Fibril Assembly by Nanobody-Gold Nanoparticle Conjugates.
Sign Up to like & getrecommendations! Published in 2019 at "Bioconjugate chemistry"
DOI: 10.1021/acs.bioconjchem.8b00797
Abstract: Amyloid fibril assembly is associated with many human disorders, and to approach an inhibitor of amyloid formation that is effective at ultralow stoichiometric concentrations remains a big challenge. Taking fibril assembly of human islet amyloid… read more here.
Keywords: fibril assembly; inhibition; iapp; amyloid fibril ... See more keywords
Amyloid Fibril Formation of Arctic Amyloid-β 1–42 Peptide is Efficiently Inhibited by the BRICHOS Domain
Sign Up to like & getrecommendations! Published in 2022 at "ACS Chemical Biology"
DOI: 10.1021/acschembio.2c00344
Abstract: Amyloid-β peptide (Aβ) aggregation is one of the hallmarks of Alzheimer’s disease (AD). Mutations in Aβ are associated with early onset familial AD, and the Arctic mutant E22G (Aβarc) is an extremely aggregation-prone variant. Here,… read more here.
Keywords: fibril; amyloid peptide; peptide; fibril formation ... See more keywords
Elucidating Important Sites and the Mechanism for Amyloid Fibril Formation by Coarse-Grained Molecular Dynamics.
Sign Up to like & getrecommendations! Published in 2017 at "ACS chemical neuroscience"
DOI: 10.1021/acschemneuro.6b00331
Abstract: Fibrils formed by the β-amyloid (Aβ) peptide play a central role in the development of Alzheimer's disease. In this study, the principles governing their growth and stability are investigated by analyzing canonical and replica-exchange molecular… read more here.
Keywords: molecular dynamics; coarse grained; fibril; monomer ... See more keywords
The hereditary mutation G51D unlocks a distinct fibril strain transmissible to wild-type α-synuclein
Sign Up to like & getrecommendations! Published in 2021 at "Nature Communications"
DOI: 10.1038/s41467-021-26433-2
Abstract: α-Synuclein (α-Syn) can form different fibril strains with distinct polymorphs and neuropathologies, which is associated with the clinicopathological variability in synucleinopathies. How different α-syn fibril strains are produced and selected under disease conditions remains poorly… read more here.
Keywords: fibril strain; g51d; fibril; hereditary mutation ... See more keywords
High-throughput discovery of fluoroprobes that recognize amyloid fibril polymorphs
Sign Up to like & getrecommendations! Published in 2025 at "Nature Chemistry"
DOI: 10.1038/s41557-025-01889-7
Abstract: Aggregation of microtubule-associated protein tau into conformationally distinct fibrils underpins neurodegenerative tauopathies. Fluorescent probes (fluoroprobes) such as thioflavin T have been essential tools for studying tau aggregation; however, most of them do not discriminate between… read more here.
Keywords: high throughput; polymorphs; amyloid fibril; fibril polymorphs ... See more keywords
Polysaccharide-reinforced amyloid fibril hydrogels and aerogels.
Sign Up to like & getrecommendations! Published in 2021 at "Nanoscale"
DOI: 10.1039/d1nr03133c
Abstract: β-Lactoglobulin amyloid fibrils are bio-colloids of high interest in many fields (e.g. water purification, cell growth, drug delivery and sensing). While the mechanical properties of pure amyloid fibril gels meet the needs of some applications,… read more here.
Keywords: reinforced amyloid; hydrogels aerogels; fibril hydrogels; amyloid fibril ... See more keywords