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Published in 2023 at "ACS chemical neuroscience"
DOI: 10.1021/acschemneuro.3c00014
Abstract: Both senile plaques formed by amyloid-β (Aβ) and neurofibrillary tangles (NFTs) comprised of tau are pathological hallmarks of Alzheimer's disease (AD). The accumulation of NFTs better correlates with the loss of cognitive function than senile…
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Keywords:
microtubule binding;
fibril seed;
preformed amyloid;
seed ... See more keywords