Targeting the amyloid-β fibril surface by constrained helical peptide inhibitor.
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DOI: 10.1021/acs.biochem.9b00800
Abstract: Amyloid-β (Aβ) oligomers are well-known toxic molecular species associated with Alzheimer's disease. Recent discoveries of the ability of amyloid fibril surfaces to convert soluble proteins into toxic oligomers suggested that these surfaces could serve as… read more here.
Keywords: helical peptide; surface; fibril surface; amyloid fibril ... See more keywords