Nascent Pre-rRNA Sorting via Phase Separation Drives the Assembly of Dense Fibrillar Components in the Human Nucleolus.
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DOI: 10.1016/j.molcel.2019.08.014
Abstract: Fibrillar centers (FCs) and dense fibrillar components (DFCs) are essential morphologically distinct sub-regions of mammalian cell nucleoli for rDNA transcription and pre-rRNA processing. Here, we report that a human nucleolus consists of several dozen FC/DFC… read more here.
Keywords: rrna; pre rrna; human nucleolus; fibrillar components ... See more keywords