Serum levels of glial fibrillary acidic protein in patients with amyotrophic lateral sclerosis
Sign Up to like & getrecommendations! Published in 2022 at "Annals of Clinical and Translational Neurology"
DOI: 10.1002/acn3.51708
Abstract: To compare serum levels of the astrocyte biomarker glial fibrillary acidic protein (GFAP) in patients with amyotrophic lateral sclerosis (ALS) and neurologically healthy controls and to analyze the relations between serum GFAP (sGFAP) and phenotype… read more here.
Keywords: patients amyotrophic; fibrillary acidic; serum levels; acidic protein ... See more keywords
Assessment of Glial Fibrillary Acidic Protein Binding to the Surface of Leukocytes with Dark‐Field Imaging and Computational Analysis
Sign Up to like & getrecommendations! Published in 2021 at "Advanced Functional Materials"
DOI: 10.1002/adfm.202009229
Abstract: The glial fibrillary acidic protein (GFAP) is widely established as a traumatic brain injury (TBI) biomarker and can be used in early diagnosis. As essential primary human immune cells, leukocytes are recruited to injured cerebral… read more here.
Keywords: glial fibrillary; field; field imaging; acidic protein ... See more keywords
Serum Glial Fibrillary Acidic Protein: A Neuromyelitis Optica Spectrum Disorder Biomarker
Sign Up to like & getrecommendations! Published in 2021 at "Annals of Neurology"
DOI: 10.1002/ana.26067
Abstract: Blood tests to monitor disease activity, attack severity, or treatment impact in neuromyelitis optica spectrum disorder (NMOSD) have not been developed. This study investigated the relationship between serum glial fibrillary acidic protein (sGFAP) concentration and… read more here.
Keywords: serum glial; spectrum disorder; fibrillary acidic; neuromyelitis optica ... See more keywords
Neurochemical regulation of the expression and function of glial fibrillary acidic protein in astrocytes
Sign Up to like & getrecommendations! Published in 2019 at "Glia"
DOI: 10.1002/glia.23734
Abstract: Glial fibrillary acidic protein (GFAP), a type III intermediate filament, is a marker of mature astrocytes. The expression of GFAP gene is regulated by many transcription factors (TFs), mainly Janus kinase‐2/signal transducer and activator of… read more here.
Keywords: fibrillary acidic; acidic protein; expression; glial fibrillary ... See more keywords
Ezrin deficiency triggers glial fibrillary acidic protein upregulation and a distinct reactive astrocyte phenotype
Sign Up to like & getrecommendations! Published in 2022 at "Glia"
DOI: 10.1002/glia.24253
Abstract: Astrocytes are increasingly being recognized as contributors to physiological brain function and behavior. Astrocytes engage in glia‐synaptic interactions through peripheral astrocyte processes, thus modulating synaptic signaling, for example, by handling glutamate removal from the synaptic… read more here.
Keywords: fibrillary acidic; ezrin; protein upregulation; acidic protein ... See more keywords
The cysteine residue of glial fibrillary acidic protein is a critical target for lipoxidation and required for efficient network organization
Sign Up to like & getrecommendations! Published in 2018 at "Free Radical Biology and Medicine"
DOI: 10.1016/j.freeradbiomed.2018.04.007
Abstract: ABSTRACT The type III intermediate filament protein glial fibrillary acidic protein (GFAP) contributes to the homeostasis of astrocytes, where it co‐polymerizes with vimentin. Conversely, alterations in GFAP assembly or degradation cause intracellular aggregates linked to… read more here.
Keywords: cysteine; fibrillary acidic; acidic protein; glial fibrillary ... See more keywords
Serum glial fibrillary acidic protein is a body fluid biomarker: A valuable prognostic for neurological disease - A systematic review.
Sign Up to like & getrecommendations! Published in 2022 at "International immunopharmacology"
DOI: 10.1016/j.intimp.2022.108624
Abstract: Astrocytes are the most abundant cell type in the human central nervous system, and they play an important role in the regulation of neuronal physiology. In neurological disorders, astrocyte disintegration leads to the release of… read more here.
Keywords: biomarker; glial fibrillary; disease; acidic protein ... See more keywords
Clinical, neuroradiological, diagnostic and prognostic profile of autoimmune glial fibrillary acidic protein astrocytopathy: A pooled analysis of 324 cases from published data and a single-center retrospective study
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Neuroimmunology"
DOI: 10.1016/j.jneuroim.2021.577718
Abstract: Autoimmune glial fibrillary acidic protein (GFAP) astrocytopathy is a recently defined autoimmune meningoencephalomyelitis, associated with GFAP-IgG antibody. A pooled analysis of 324 cases from published literature and a retrospective single-center study were performed, firstly reveals… read more here.
Keywords: fibrillary acidic; analysis 324; acidic protein; glial fibrillary ... See more keywords
Autoimmune glial fibrillary acidic protein astrocytopathy resembling isolated central nervous system lymphomatoid granulomatosis
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Neuroimmunology"
DOI: 10.1016/j.jneuroim.2021.577748
Abstract: We report two patients with meningoencephalomyelitis without evidence of extra central nervous system (CNS) involvement. Brain MRI showed linear perivascular radial gadolinium enhancement patterns and spinal cord MRI showed longitudinal extensive T2-hyperintensity lesions. Pathological findings… read more here.
Keywords: nervous system; central nervous; fibrillary acidic; acidic protein ... See more keywords
Pediatric glial fibrillary acidic protein meningoencephalomyelitis: A case report and review of the literature.
Sign Up to like & getrecommendations! Published in 2019 at "Multiple sclerosis and related disorders"
DOI: 10.1016/j.msard.2018.12.008
Abstract: A novel autoantibody, glial fibrillary acidic protein (GFAP)-IgG, has recently been associated with cases of meningoencephalomyelitis. This entity is still being unraveled. Very few pediatric patients have been identified; thus, the clinical, biological and imaging… read more here.
Keywords: acidic protein; review literature; glial fibrillary; fibrillary acidic ... See more keywords
MRI features and evolution of autoimmune glial fibrillary acidic protein astrocytopathy: A retrospective cross-sectional and longitudinal study.
Sign Up to like & getrecommendations! Published in 2022 at "Multiple sclerosis and related disorders"
DOI: 10.1016/j.msard.2022.103512
Abstract: BACKGROUND Autoimmune glial fibrillary acidic protein astrocytopathy (AGA) is a relatively novel disease. The early diagnosis of this inflammatory central nervous system (CNS) disorder remains challenging. OBJECTIVES We aimed to explore the imaging manifestations and… read more here.
Keywords: autoimmune glial; glial fibrillary; fibrillary acidic; acidic protein ... See more keywords