Tau fibrils evade autophagy by excessive p62 coating and TAX1BP1 exclusion
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DOI: 10.1126/sciadv.adm8449
Abstract: The accumulation of protein aggregates is a hallmark of many diseases, including Alzheimer’s disease. As a major pillar of the proteostasis network, autophagy mediates the degradation of protein aggregates. The autophagy cargo receptor p62 recognizes… read more here.
Keywords: fibrils evade; tau fibrils; tau; protein aggregates ... See more keywords