Nematic Fibrin Fibers Enabling Vascularized Thrombus Implants Facilitate Scarless Cutaneous Wound Healing.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced materials"
DOI: 10.1002/adma.202211149
Abstract: Autologous implantable scaffolds that induce vasculogenesis have shown great potential in tissue regeneration; however, previous attempts mainly relied on cell-laden hydrogel patches using fat tissues or platelet-rich plasma, which are insufficient for generating a uniform… read more here.
Keywords: nematic fibrin; fibers enabling; wound healing; enabling vascularized ... See more keywords
Strength, Deformability and Toughness of Uncrosslinked Fibrin Fibers from Theoretical Reconstruction of Stress-Strain Curves.
Sign Up to like & getrecommendations! Published in 2021 at "Acta biomaterialia"
DOI: 10.1016/j.actbio.2021.09.050
Abstract: Structural mechanisms underlying the mechanical properties of fibrin fibers are elusive. We combined tensile testing of uncrosslinked fibrin polymers in vitro and in silico to explore their material properties. The experimental stress (σ) - strain… read more here.
Keywords: uncrosslinked fibrin; rupture; fibrin fibers; protofibril ... See more keywords
Fracture mechanics analysis of fibrin fibers using mesoscale and continuum level methods
Sign Up to like & getrecommendations! Published in 2021 at "Informatics in medicine unlocked"
DOI: 10.1016/j.imu.2021.100524
Abstract: Computational models for simulating and predicting fibrin fiber fracture are important tools for studying bulk mechanical properties and mechanobiological response of fibrin networks in physiological conditions. In this work, we employed a new strategy to… read more here.
Keywords: fracture; fibrin fibers; fibrin; fibrin fiber ... See more keywords
A mathematical model of plasmin-mediated fibrinolysis of single fibrin fibers
Sign Up to like & getrecommendations! Published in 2024 at "PLOS Computational Biology"
DOI: 10.1371/journal.pcbi.1012684
Abstract: Fibrinolysis, the plasmin-mediated degradation of the fibrin mesh that stabilizes blood clots, is an important physiological process, and understanding mechanisms underlying lysis is critical for improved stroke treatment. Experimentalists are now able to study lysis… read more here.
Keywords: plasmin mediated; fibrin fibers; model; fibrinolysis ... See more keywords
The Applicability of Current Turbidimetric Approaches for Analyzing Fibrin Fibers and Other Filamentous Networks
Sign Up to like & getrecommendations! Published in 2022 at "Biomolecules"
DOI: 10.3390/biom12060807
Abstract: Turbidimetry is an experimental technique often used to study the structure of filamentous networks. To extract structural properties such as filament diameter from turbidimetric data, simplifications to light scattering theory must be employed. In this… read more here.
Keywords: applicability current; analyzing fibrin; filamentous networks; fibrin fibers ... See more keywords