Soft matrices downregulate FAK activity to promote growth of tumor-repopulating cells.
Sign Up to like & getrecommendations! Published in 2017 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2016.12.122
Abstract: Tumor-repopulating cells (TRCs) are a tumorigenic sub-population of cancer cells that drives tumorigenesis. We have recently reported that soft fibrin matrices maintain TRC growth by promoting histone 3 lysine 9 (H3K9) demethylation and Sox2 expression… read more here.
Keywords: tumor repopulating; repopulating cells; fibrin matrices; h3k9 methylation ... See more keywords
Distribution and quantification of activated platelets in platelet-rich fibrin matrices.
Sign Up to like & getrecommendations! Published in 2020 at "Platelets"
DOI: 10.1080/09537104.2020.1856359
Abstract: Platelet-rich fibrin (PRF) has been widely applied in regenerative therapy owing to its simple preparation protocol. To date, the original protocol for preparing leukocyte-rich (L)-PRF has been modified to produce derivatives such as advanced (A)-PRF,… read more here.
Keywords: platelet rich; fibrin matrices; activated platelets; rich fibrin ... See more keywords