Fibrinogen regulates lesion border‐forming reactive astrocyte properties after vascular damage
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DOI: 10.1002/glia.24166
Abstract: Reactive astrocytes at the border of damaged neuronal tissue organize into a barrier surrounding the fibrotic lesion core, separating this central region of inflammation and fibrosis from healthy tissue. Astrocytes are essential to form the… read more here.
Keywords: fibrinogen; lesion border; border; border forming ... See more keywords
Fibrinogen as an independent predictor of mortality in decompensated cirrhosis and bleeding
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DOI: 10.1002/hep.28915
Abstract: The study by Drolz et al. is important given the need to reduce bleeding complications and mortality in decompensated cirrhosis. The novel finding of this study was that fibrinogen is independently predictive of new onset… read more here.
Keywords: fibrinogen; study; bleeding; mortality ... See more keywords
Myeloperoxidase‐induced fibrinogen unfolding and clotting
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DOI: 10.1002/jemt.24107
Abstract: Due to its unique properties and high biomedical relevance fibrinogen is a promising protein for the development of various matrixes and scaffolds for biotechnological applications. Fibrinogen molecules may form extensive clots either upon specific cleavage… read more here.
Keywords: fibrinogen clotting; myeloperoxidase induced; fibrinogen; induced fibrinogen ... See more keywords
Principles of Fibrinogen Fiber Assembly In Vitro.
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DOI: 10.1002/mabi.202000412
Abstract: Fibrinogen nanofibers hold great potential for applications in wound healing and personalized regenerative medicine due to their ability to mimic the native blood clot architecture. Although versatile strategies exist to induce fibrillogenesis of fibrinogen in… read more here.
Keywords: fiber assembly; principles fibrinogen; fibrinogen; vitro ... See more keywords
A Commercial Non-Binding Surface Effectively Reduces Fibrinogen Adsorption but Does Not Prevent Platelet Adhesion to Fibrinogen.
Sign Up to like & getrecommendations! Published in 2023 at "Macromolecular bioscience"
DOI: 10.1002/mabi.202300052
Abstract: A commercial non-binding surface effectively prevents protein adsorption, however, the platelet phenotype on this surface has yet to be defined. This study evaluates platelet adhesion and adsorption of several plasma/extra-cellular matrix (ECM) proteins to the… read more here.
Keywords: binding surface; adsorption; fibrinogen; platelet adhesion ... See more keywords
Inverse agonist of ERRγ reduces cannabinoid receptor type 1-mediated induction of fibrinogen synthesis in mice with a high-fat diet-intoxicated liver
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DOI: 10.1007/s00204-018-2270-4
Abstract: Upon liver intoxication with malnutrition or high-fat diet feeding, fibrinogen is synthesized by hepatocytes and secreted into the blood in human and mouse. Its primary function is to occlude blood vessels upon damage and thereby… read more here.
Keywords: fat diet; inverse agonist; fibrinogen; high fat ... See more keywords
Prognostic significance of hyperfibrinogenemia in patients with lower-risk myelodysplastic syndromes
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DOI: 10.1007/s00277-019-03863-z
Abstract: Dear Editor, Fibrinogen is a protein produced following inflammation, and hyperfibrinogenemia is known as a poor prognostic factor in various tumors. In recent years, it has also been reported that hyperfibrinogenemia is a poor prognostic… read more here.
Keywords: patients lower; fibrinogen; year; lower risk ... See more keywords
Is it required to routinely check fibrinogen level in patients with rheumatic diseases on tocilizumab? Case-based review
Sign Up to like & getrecommendations! Published in 2019 at "Rheumatology International"
DOI: 10.1007/s00296-019-04268-x
Abstract: Tocilizumab (TCZ) may rarely cause hematological side effects including neutropenia and thrombocytopenia. TCZ is essentially expected to lower the fibrinogen levels to stay within the normal range, but TCZ-induced hypofibrinogenemia has been rarely reported in… read more here.
Keywords: fibrinogen; tcz; routinely check; review ... See more keywords
Significant genetic association of a functional TFPI variant with circulating fibrinogen levels and coronary artery disease
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DOI: 10.1007/s00438-017-1365-6
Abstract: The tissue factor pathway inhibitor (TFPI) gene encodes a protease inhibitor with a critical role in regulation of blood coagulation. Some genomic variants in TFPI were previously associated with plasma TFPI levels, however, it remains… read more here.
Keywords: association; fibrinogen levels; tfpi variant; fibrinogen ... See more keywords
Response to letter to the editor regarding “A retrospective study of the effect of fibrinogen levels during fresh frozen plasma transfusion in patients with traumatic brain injury”
Sign Up to like & getrecommendations! Published in 2019 at "Acta Neurochirurgica"
DOI: 10.1007/s00701-019-04078-x
Abstract: Dear Editor, We thankWang et al. for their interesting comments on our article, “A retrospective study of the effect of fibrinogen levels during fresh frozen plasma transfusion in patients with traumatic brain injury” [3]. In… read more here.
Keywords: traumatic brain; fibrinogen; hematoma; transfusion ... See more keywords
Systemic Low-grade Inflammation and depressive symptomology at chronic phase of ischemic stroke: The Chain Mediating Role of Fibrinogen and Neutrophil counts
Sign Up to like & getrecommendations! Published in 2021 at "Brain, behavior, and immunity"
DOI: 10.1016/j.bbi.2021.10.011
Abstract: BACKGROUND Post-stroke depression (PSD) is the most common psychological consequence among stroke patients. Increased inflammatory markers resulted from ischemic stroke probably played an important role in pathogenesis of depressive symptomology. We aimed to determine the… read more here.
Keywords: depressive symptomology; ischemic stroke; fibrinogen; year ... See more keywords