Cost-effectiveness of Fibrinogen Concentrate vs Cryoprecipitate for Treating Acquired Hypofibrinogenemia in Bleeding Adult Cardiac Surgical Patients
Sign Up to like & getrecommendations! Published in 2023 at "JAMA Surgery"
DOI: 10.1001/jamasurg.2022.6818
Abstract: This study attempts to determine cost-effectiveness of fibrinogen concentrate vs cryoprecipitate for managing active bleeding in adult patients who underwent cardiac surgery. read more here.
Keywords: bleeding adult; concentrate cryoprecipitate; fibrinogen concentrate; effectiveness fibrinogen ... See more keywords
Real-life experiences with goal-directed prohemostatic therapy with fibrinogen concentrate, prothrombin complex concentrate, and recombinant factor VIIa: a retrospective study of 287 consecutive patients
Sign Up to like & getrecommendations! Published in 2022 at "Scandinavian Journal of Clinical and Laboratory Investigation"
DOI: 10.1080/00365513.2022.2040048
Abstract: Abstract The Danish Capital Region Blood Bank operates a 24/7 on-call service staffed with physicians specialized in hemostatic management to guide clinicians in hemostatic resuscitation, including administration of prohemostatic therapy (PHT). The outcome of patients… read more here.
Keywords: complex concentrate; fibrinogen concentrate; concentrate; recombinant factor ... See more keywords
Effect of fibrinogen concentrate administration on early mortality in traumatic hemorrhagic shock: A propensity score analysis
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Trauma and Acute Care Surgery"
DOI: 10.1097/ta.0000000000002624
Abstract: Supplemental digital content is available in the text. BACKGROUND Fibrinogen concentrate is widely used in traumatic hemorrhagic shock despite weak evidence in the literature. The aim of the study was to evaluate the effect of… read more here.
Keywords: hemorrhagic shock; fibrinogen concentrate;
Fibrinogen supplementation for the trauma patient: Should you choose fibrinogen concentrate over cryoprecipitate?
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Trauma and Acute Care Surgery"
DOI: 10.1097/ta.0000000000003728
Abstract: Fibrinogen supplementation for bleeding trauma patients using fibrinogen concentrate instead of cryoprecipitate is associated with earlier fibrinogen administration and improved outcomes. BACKGROUND Trauma-induced coagulopathy is frequently associated with hypofibrinogenemia. Cryoprecipitate (Cryo), and fibrinogen concentrate (FC)… read more here.
Keywords: fibrinogen concentrate; cryoprecipitate; trauma; fibrinogen ... See more keywords
The role of fibrinogen and fibrinogen concentrate in cardiac surgery: an international consensus statement from the Haemostasis and Transfusion Scientific Subcommittee of the European Association of Cardiothoracic Anaesthesiology
Sign Up to like & getrecommendations! Published in 2019 at "Anaesthesia"
DOI: 10.1111/anae.14842
Abstract: To date, data regarding the efficacy and safety of administering fibrinogen concentrate in cardiac surgery are limited. Studies are limited by their low sample size and large heterogeneity with regard to the patient population, by… read more here.
Keywords: cardiac surgery; fibrinogen concentrate; fibrinogen; anaesthesiology ... See more keywords
Congenital bleeding disorders: Report from one tertiary centre in Guatemala
Sign Up to like & getrecommendations! Published in 2018 at "Haemophilia"
DOI: 10.1111/hae.13416
Abstract: 1. Casini A, de Moerloose P, Neerman-Arbez M. Clinical features and management of congenital fibrinogen deficiencies. Semin Thromb Hemost. 2016;42:366-374. 2. Peyvandi F, Palla R. Fibrinogen concentrates. Clin Adv Hematol Oncol. 2009;7:788-790. 3. Mensah PK,… read more here.
Keywords: congenital bleeding; fibrinogen; bleeding disorders; fibrinogen concentrate ... See more keywords
Fibrinogen concentrate for perioperative bleeding: what can we learn from the clinical trials?
Sign Up to like & getrecommendations! Published in 2019 at "Transfusion"
DOI: 10.1111/trf.15437
Abstract: There is great variation in the study design of the 21 major randomized controlled trials assessing fibrinogen concentrate use in perioperative settings, thus making it a confusing landscape to draw definitive conclusions about the efficacy… read more here.
Keywords: perioperative bleeding; fibrinogen concentrate; bleeding; learn clinical ... See more keywords
Efficacy and safety of fibrinogen concentrate for perioperative prophylaxis of bleeding in adult, adolescent, and pediatric patients with congenital fibrinogen deficiency: FORMA‐02 and FORMA‐04 clinical trials
Sign Up to like & getrecommendations! Published in 2022 at "Transfusion"
DOI: 10.1111/trf.17029
Abstract: Congenital fibrinogen deficiency (CFD) is a rare coagulation disorder placing patients at increased bleeding risk. Human fibrinogen concentrate (HFC) represents current standard of care for fibrinogen replacement in CFD, however, limited data are available on… read more here.
Keywords: adolescent pediatric; fibrinogen concentrate; congenital fibrinogen; adult adolescent ... See more keywords
875 Does fibrinogen concentrate improve outcomes in major traumatic haemorrhage? A systematic review
Sign Up to like & getrecommendations! Published in 2022 at "Emergency Medicine Journal"
DOI: 10.1136/emermed-2022-rcem.35
Abstract: Background Acute traumatic coagulopathy (ATC) is present in a quarter of severely injured patients and is associated with worse outcomes.(1–3) Fibrinogen is the first clotting protein to become deficient in ATC and there is a… read more here.
Keywords: fibrinogen concentrate; traumatic haemorrhage; review; fibrinogen ... See more keywords
Fibrinogen Concentrate for the Treatment of Thrombolysis-Associated Hemorrhage in Adult Ischemic Stroke Patients
Sign Up to like & getrecommendations! Published in 2020 at "Clinical and Applied Thrombosis/Hemostasis"
DOI: 10.1177/1076029620951867
Abstract: In patients with ischemic stroke who receive systemic recombinant tissue plasminogen activator (rt-PA), the risk of secondary hemorrhage is 1-7%. Fibrinogen supplementation with cryoprecipitate is recommended in patients with rt-PA-associated symptomatic hemorrhage. We examined whether… read more here.
Keywords: ischemic stroke; fibrinogen; fibrinogen concentrate; hemorrhage ... See more keywords
Fibrinogen Concentrate Vs Cryoprecipitate in Pseudomyxoma Peritonei Surgery: Interim Results from a Prospective, Randomized, Controlled Phase 2 Study
Sign Up to like & getrecommendations! Published in 2018 at "Blood"
DOI: 10.1182/blood-2018-99-118145
Abstract: Introduction: Pseudomyxoma peritonei (PMP) is a rare entity that usually results from a perforated primary appendiceal tumor. The established intervention for PMP is cytoreductive surgery with hyperthermic intraperitoneal chemotherapy (Sugarbaker procedure). Acquired fibrinogen deficiency and… read more here.
Keywords: surgery; fibrinogen; cryoprecipitate; fibrinogen concentrate ... See more keywords