Soluble Fibrinogen–Like Protein 2 Downregulation and Th17/Treg Imbalance in a Taurocholate‐Induced Murine Experimental Model of Severe Acute Pancreatitis
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.25076
Abstract: Severe acute pancreatitis (SAP) is associated with tremendous systemic inflammation, T‐helper 17 (Th17) cells, and regulatory T (Treg) cells play an essential role in the inflammatory responses. Meanwhile, soluble fibrinogen–like protein 2 (Sfgl2) is a… read more here.
Keywords: like protein; fibrinogen like; soluble fibrinogen; treg ... See more keywords
Increased expression of Fibrinogen-Like Protein 2 is associated with poor prognosis in patients with clear cell renal cell carcinoma
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-13149-x
Abstract: Fibrinogen-like protein 2 (FGL2) is highly expressed in various tumour tissues and plays a vital role in tumour initiation and progression. This study evaluated the clinical significance of FGL2 in patients with clear cell renal… read more here.
Keywords: like protein; fgl2 expression; fibrinogen like; expression ... See more keywords
Preliminary exploration of the role of fibrinogen-like protein 2 in neuroblastoma
Sign Up to like & getrecommendations! Published in 2025 at "Scientific Reports"
DOI: 10.1038/s41598-025-26272-x
Abstract: Fibrinogen-like protein 2 (FGL2) has been reported to modulate the tumor microenvironment and play critical roles in the initiation and progression of various tumors. However, its role and underlying mechanisms in neuroblastoma remain unclear. This… read more here.
Keywords: fgl2; neuroblastoma; fibrinogen like; like protein ... See more keywords
Up-regulation of fibrinogen-like protein 2 in porcine endothelial cells by xenogeneic CD40 signal
Sign Up to like & getrecommendations! Published in 2018 at "Animal Cells and Systems"
DOI: 10.1080/19768354.2018.1433718
Abstract: ABSTRACT Acute humoral xenograft rejection (AHXR), characterized by thrombin generation and endothelial cell activation, should be overcome for the success of xenotransplantation. Fibrinogen-like protein 2 (fgl2) expressed on endothelial cells can convert prothrombin to thrombin… read more here.
Keywords: like protein; fgl2 expression; fibrinogen like; endothelial cells ... See more keywords
Exosomes derived from fibrinogen-like protein 1-overexpressing bone marrow-derived mesenchymal stem cells ameliorates rheumatoid arthritis
Sign Up to like & getrecommendations! Published in 2022 at "Bioengineered"
DOI: 10.1080/21655979.2022.2090379
Abstract: ABSTRACT Rheumatoid arthritis (RA) is a most common chronic joint disease belonging to inflammatory autoimmune disease. The aim of this study was to determine the role and mechanism of bone marrow mesenchymal stem cells (BMSCs)-derived… read more here.
Keywords: fibrinogen like; bone marrow; fgl1 exos; rheumatoid arthritis ... See more keywords
Fibrinogen‐like protein 2 contributes to normal murine cardiomyocyte maturation and heart development
Sign Up to like & getrecommendations! Published in 2021 at "Experimental Physiology"
DOI: 10.1113/ep089450
Abstract: What is the central question of this study? What is the role of fibrinogen‐like protein 2 (FGL2) in murine cardiomyocyte maturation? What is the main finding and its importance? This is the first study showing… read more here.
Keywords: fibrinogen like; like protein; cardiomyocyte; cardiomyocyte maturation ... See more keywords
Presence and activity of Fibrinogen like protein 2 in platelets
Sign Up to like & getrecommendations! Published in 2023 at "PLOS ONE"
DOI: 10.1371/journal.pone.0285735
Abstract: Background Fibrinogen-like protein 2 (FGL2) is a serine protease capable of converting prothrombin into thrombin (i.e., prothrombinase-like activity) while bypassing the classic coagulation cascade. It has been reported to be expressed by mononuclear blood cells… read more here.
Keywords: fibrinogen like; activity; like protein; blood ... See more keywords
Fibrinogen-Like Protein 1 as a Novel Biomarker of Psoriasis Severity
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Inflammation Research"
DOI: 10.2147/jir.s378953
Abstract: Background Psoriasis is an immune-mediated chronic systemic inflammatory skin disease whose diagnosis and severity assessment pose challenges for clinicians worldwide. The use of serum biomarkers facilitates the early diagnosis and treatment of psoriasis. Methods This… read more here.
Keywords: fibrinogen like; like protein; psoriasis; severity ... See more keywords
Fibrinogen-Like Protein 1 Serves as an Anti-Inflammatory Agent for Collagen-Induced Arthritis Therapy in Mice
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2021.767868
Abstract: Fibrinogen-like protein 1 (FGL1) was recently identified as a major ligand of lymphocyte-activation gene-3 (LAG-3) on activated T cells and serves as an immune suppressive molecule for regulation of immune homeostasis. However, whether FGL1 has… read more here.
Keywords: fgl1; induced arthritis; fibrinogen like; collagen induced ... See more keywords
Fibrinogen, Fibrinogen-like 1 and Fibrinogen-like 2 Proteins, and Their Effects
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DOI: 10.3390/biomedicines10071712
Abstract: Fibrinogen (Fg) and its derivatives play a considerable role in many diseases. For example, increased levels of Fg have been found in many inflammatory diseases, such as Alzheimer’s disease, multiple sclerosis, traumatic brain injury, rheumatoid… read more here.
Keywords: like proteins; fibrinogen fibrinogen; fibrinogen like; like fibrinogen ... See more keywords
Fibrinogen-like Protein 1 as a Predictive Marker for the Incidence of Severe Acute Pancreatitis and Infectious Pancreatic Necrosis
Sign Up to like & getrecommendations! Published in 2022 at "Medicina"
DOI: 10.3390/medicina58121753
Abstract: Background and Objectives: Acute pancreatitis (AP) is defined as an acute inflammatory disorder of the pancreas and is a common gastrointestinal disease. Since currently used indicators lack specifics and cannot accurately reflect the phase of… read more here.
Keywords: fibrinogen like; fgl; pancreatic necrosis; like protein ... See more keywords