Enhanced migration of murine fibroblast-like 3T3-L1 preadipocytes on type I collagen-coated dish is reversed by silibinin treatment
Sign Up to like & getrecommendations! Published in 2017 at "Molecular and Cellular Biochemistry"
DOI: 10.1007/s11010-017-3173-z
Abstract: Migration of fibroblast-like preadipocytes is important for the development of adipose tissue, whereas excessive migration is often responsible for impaired adipose tissue related with obesity and fibrotic diseases. Type I collagen (collagen I) is the… read more here.
Keywords: collagen; fibroblast; enhanced migration; migration ... See more keywords
Zinc oxide nanoparticles induce human tenon fibroblast apoptosis through reactive oxygen species and caspase signaling pathway.
Sign Up to like & getrecommendations! Published in 2020 at "Archives of biochemistry and biophysics"
DOI: 10.1016/j.abb.2020.108324
Abstract: Glaucoma is the leading cause of irreversible blindness in the world and trabeculectomy remains still the most commonly performed filtration surgery. Failure of trabeculectomy is due to the formation of scarring, which is associated with… read more here.
Keywords: caspase; fibroblast; apoptosis; zinc oxide ... See more keywords
DNA methyltransferase-1 inactivation of androgen receptor axis triggers homocysteine induced cardiac fibroblast autophagy in diabetic cardiac fibrosis.
Sign Up to like & getrecommendations! Published in 2020 at "Archives of biochemistry and biophysics"
DOI: 10.1016/j.abb.2020.108521
Abstract: Diabetic cardiac fibrosis is one of the main pathological manifestations of diabetic cardiomyopathy (DCM). Cardiac fibroblast autophagy plays critical roles in diabetic cardiac fibrosis, however, the underlying mechanism of cardiac fibroblast autophagy and diabetic cardiac… read more here.
Keywords: diabetic cardiac; fibroblast; cardiac fibroblast; cardiac fibrosis ... See more keywords
Mechanosensing dysregulation in the fibroblast: A hallmark of the aging heart
Sign Up to like & getrecommendations! Published in 2020 at "Ageing Research Reviews"
DOI: 10.1016/j.arr.2020.101150
Abstract: The myofibroblast is a specialized fibroblast that expresses α-smooth muscle actin (α-SMA) and participates in wound contraction and fibrosis. The fibroblast to myofibroblast transition depends on chemical and mechanical signals. A fibroblast senses the changes… read more here.
Keywords: dysregulation fibroblast; fibroblast; aging heart; fibroblast hallmark ... See more keywords
Identity Noise and Adipogenic Traits Characterize Dermal Fibroblast Aging
Sign Up to like & getrecommendations! Published in 2018 at "Cell"
DOI: 10.1016/j.cell.2018.10.012
Abstract: During aging, stromal functions are thought to be impaired, but little is known whether this stems from changes of fibroblasts. Using population- and single-cell transcriptomics, as well as long-term lineage tracing, we studied whether murine… read more here.
Keywords: traits characterize; fibroblast; noise adipogenic; adipogenic traits ... See more keywords
Lipophilic tracer Dil and fluorescence labeling of acridine orange used for Leishmania major tracing in the fibroblast cells
Sign Up to like & getrecommendations! Published in 2019 at "Heliyon"
DOI: 10.1016/j.heliyon.2019.e03073
Abstract: Background This study aims to evaluate the use of fluorescent dye Dil and super vital dye acridine orange (AO) in vitro tracking of labeled L. major in the fibroblast cells. Methods Dil crystal and AO… read more here.
Keywords: fibroblast cells; fluorescence; fibroblast; dil ... See more keywords
Therapeutic effects of eperisone on pulmonary fibrosis via preferential suppression of fibroblast activity
Sign Up to like & getrecommendations! Published in 2022 at "Cell Death Discovery"
DOI: 10.1038/s41420-022-00851-7
Abstract: Although the exact pathogenesis of idiopathic pulmonary fibrosis (IPF) is still unknown, the transdifferentiation of fibroblasts into myofibroblasts and the production of extracellular matrix components such as collagen, triggered by alveolar epithelial cell injury, are… read more here.
Keywords: fibroblast; ll29 cells; pulmonary fibrosis; alveolar epithelial ... See more keywords
Human and murine fibroblast single cell transcriptomics reveals fibroblast clusters are differentially affected by ageing, and serum cholesterol.
Sign Up to like & getrecommendations! Published in 2023 at "Cardiovascular research"
DOI: 10.1093/cvr/cvad016
Abstract: AIMS Specific fibroblast markers and in-depth heterogeneity analysis are currently lacking, hindering functional studies in cardiovascular diseases (CVD). Here, we established cell-type markers and heterogeneity in murine and human arteries and studied the adventitial fibroblast… read more here.
Keywords: fibroblast; human murine; cell transcriptomics; single cell ... See more keywords
Phenytoin sodium-ameliorated gingival fibroblast aging is associated with autophagy.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of periodontal research"
DOI: 10.1111/jre.12750
Abstract: BACKGROUND AND OBJECTIVE Human gingival fibrolasts aging is an important cause of periodontal disease. Phenytoin sodium (phenytoin) has a side effect of gingival hyperplasia and an effect on the autophagy progress. This study investigated whether… read more here.
Keywords: fibroblast; phenytoin sodium; phenytoin; effect ... See more keywords
Sphingolipids control dermal fibroblast heterogeneity
Sign Up to like & getrecommendations! Published in 2022 at "Science"
DOI: 10.1126/science.abh1623
Abstract: Human cells produce thousands of lipids that change during cell differentiation and can vary across individual cells of the same type. However, we are only starting to characterize the function of these cell-to-cell differences in… read more here.
Keywords: dermal fibroblasts; cell; heterogeneity; fibroblast ... See more keywords
TRPM7 contributes to TGF-ß signaling in renal fibroblast
Sign Up to like & getrecommendations! Published in 2023 at "Physiology"
DOI: 10.1152/physiol.2023.38.s1.5735155
Abstract: Mammalian transient receptor potential melastatin (TRPM), the non-selective cation channel subfamily, has eight members and is extensively expressed in excitable and non-excitable cells where they perform diverse functions, including sensory transduction, magnesium reabsorption, cell adhesion,… read more here.
Keywords: fibroblast; trpm7; expression; physiology ... See more keywords