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Establishment and Characterization of an HBV Viral Spread and Infectious System following Long-Term Passage of an HBV Clinical Isolate in the Primary Human Hepatocyte and Fibroblast Coculture System

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Published in 2022 at "Journal of Virology"

DOI: 10.1128/jvi.00849-22

Abstract: The existing cell culture-based methods to study HBV have limitations and do not allow for viral long-term passage. In this study, an HBV genotype A clinical isolate was subjected to multiple rounds of UV treatment… read more here.

Keywords: long term; system; clinical isolate; passage ... See more keywords