Fibroblast heterogeneity in prostate carcinogenesis.
Sign Up to like & getrecommendations! Published in 2021 at "Cancer letters"
DOI: 10.1016/j.canlet.2021.10.028
Abstract: Our understanding of stromal components, specifically cancer-associated fibroblasts (CAF), in prostate cancer (PCa), has evolved from considering these cells as inert bystanders to acknowledging their significance as players in prostate tumorigenesis. CAF are multifaceted-they promote… read more here.
Keywords: caf; heterogeneity; heterogeneity prostate; fibroblast heterogeneity ... See more keywords
Single-cell RNA-seq reveals fibroblast heterogeneity and increased mesenchymal fibroblasts in human fibrotic skin diseases
Sign Up to like & getrecommendations! Published in 2021 at "Nature Communications"
DOI: 10.1038/s41467-021-24110-y
Abstract: Fibrotic skin disease represents a major global healthcare burden, characterized by fibroblast hyperproliferation and excessive accumulation of extracellular matrix. Fibroblasts are found to be heterogeneous in multiple fibrotic diseases, but fibroblast heterogeneity in fibrotic skin… read more here.
Keywords: single cell; fibrotic skin; fibroblast heterogeneity; skin ... See more keywords
Fibroblast Heterogeneity in Healthy and Wounded Skin.
Sign Up to like & getrecommendations! Published in 2022 at "Cold Spring Harbor perspectives in biology"
DOI: 10.1101/cshperspect.a041238
Abstract: Fibroblasts are the main cell type in the dermis. They are responsible for the synthesis and deposition of structural proteins such as collagen and elastin, which are integrated into the extracellular matrix (ECM). Mouse and… read more here.
Keywords: fibroblast heterogeneity; heterogeneity; healthy wounded; heterogeneity healthy ... See more keywords