Abstract B63: Mass cytometry identifies two distinct fibroblast lineages in pancreatic tumors that differentially regulate antitumor immunity
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DOI: 10.1158/1538-7445.panca19-b63
Abstract: Pancreatic ductal adenocarcinoma (PDA) is defined by an extensive, fibroblast-rich desmoplasia. Recent single-cell RNAseq studies in pancreatic cancer and other tumor types have described extensive transcriptional heterogeneity within the fibroblast compartment on par with the… read more here.
Keywords: mass cytometry; fibroblast; distinct fibroblast; fibroblast populations ... See more keywords
Role of distinct fibroblast lineages and immune cells in dermal repair following UV radiation induced tissue damage.
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DOI: 10.7554/elife.71052
Abstract: Solar ultraviolet radiation (UVR) is a major source of skin damage, resulting in inflammation, premature ageing and cancer. While several UVR-induced changes, including extracellular matrix reorganisation and epidermal DNA damage, have been documented, the role… read more here.
Keywords: fibroblast; damage; repair following; fibroblast lineages ... See more keywords