Mitomycin C modulates intracellular matrix metalloproteinase-9 expression and affects corneal fibroblast migration.
Sign Up to like & getrecommendations! Published in 2019 at "European journal of pharmacology"
DOI: 10.1016/j.ejphar.2019.172752
Abstract: Mitomycin C (MMC) is often used to prevent postoperative corneal haze and subconjunctival fibrosis in ocular surgery. It also affects the motility and viability of the residual ocular cells, including corneal stromal cells. Extracellular matrix… read more here.
Keywords: corneal fibroblast; matrix metalloproteinase; intracellular mmp; mmp ... See more keywords
Fibronectin promotes directional persistence in fibroblast migration through interactions with both its cell-binding and heparin-binding domains
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DOI: 10.1038/s41598-017-03701-0
Abstract: The precise mechanisms through which insoluble, cell-adhesive ligands induce and regulate directional cell migration remain obscure. We recently demonstrated that elevated surface density of physically adsorbed plasma fibronectin (FN) promotes high directional persistence in fibroblast… read more here.
Keywords: directional persistence; fibronectin promotes; migration; fibroblast migration ... See more keywords
Inhibition of Pterygium Fibroblast Migration and Outgrowth by Bevacizumab and Cyclosporine A Involves Down-Regulation of Matrix Metalloproteinases-3 and -13
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DOI: 10.1371/journal.pone.0169675
Abstract: We examined the connection between matrix metalloproteinase (MMP) expression/activity and pterygium fibroblast migration, and how these were affected by bevacizumab and/or cyclosporine A (CsA). Fibroblasts were obtained from 20 pterygia and 6 normal conjunctival specimens.… read more here.
Keywords: pterygium fibroblast; pterygium; expression mmps; migration ... See more keywords
Helium Conditioning Increases Cardiac Fibroblast Migration Which Effect Is Not Propagated via Soluble Factors or Extracellular Vesicles
Sign Up to like & getrecommendations! Published in 2021 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms221910504
Abstract: Helium inhalation induces cardioprotection against ischemia/reperfusion injury, the cellular mechanism of which remains not fully elucidated. Extracellular vesicles (EVs) are cell-derived, nano-sized membrane vesicles which play a role in cardioprotective mechanisms, but their function in… read more here.
Keywords: extracellular vesicles; migration; soluble factors; fibroblast migration ... See more keywords