Isolation of Different Dermal Fibroblast Populations from the Skin and the Hair Follicle.
Sign Up to like & getrecommendations! Published in 2020 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-0648-3_2
Abstract: The establishment of primary cells from fresh tissue is a widely used method for investigating human tissue in vitro. The skin harbors different cell populations in the dermis and the hair follicle, which can be… read more here.
Keywords: isolation; fibroblast populations; dermal fibroblast; hair follicle ... See more keywords
P158 Defining distinct fibroblast populations in systemic sclerosis skin using functional characterization and single-cell RNA sequencing
Sign Up to like & getrecommendations! Published in 2023 at "Rheumatology"
DOI: 10.1093/rheumatology/kead104.199
Abstract: Fibroblasts isolated by traditional explant culture from skin biopsies in systemic sclerosis (SSc) have a profibrotic and “migratory” phenotype. Single cell RNAseq (scRNAseq) studies suggest other fibroblast subpopulations may be important in SSc pathogenesis. We… read more here.
Keywords: skin; fibroblast populations; resident; expression ... See more keywords
Abstract B63: Mass cytometry identifies two distinct fibroblast lineages in pancreatic tumors that differentially regulate antitumor immunity
Sign Up to like & getrecommendations! Published in 2019 at "Cancer Research"
DOI: 10.1158/1538-7445.panca19-b63
Abstract: Pancreatic ductal adenocarcinoma (PDA) is defined by an extensive, fibroblast-rich desmoplasia. Recent single-cell RNAseq studies in pancreatic cancer and other tumor types have described extensive transcriptional heterogeneity within the fibroblast compartment on par with the… read more here.
Keywords: mass cytometry; fibroblast; distinct fibroblast; fibroblast populations ... See more keywords
Role of Fibroblast Populations in Periodontal Wound Healing and Tissue Remodeling
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2019.00270
Abstract: After injury to periodontal tissues, a sequentially phased healing response is initiated that enables wound closure and partial restoration of tissue structure and function. Wound closure in periodontal tissues involves the tightly regulated coordination of… read more here.
Keywords: wound healing; connective tissues; tissue; fibroblast populations ... See more keywords