Articles with "fibroblast proliferation" as a keyword



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The Mechanism of miR-222 Targets Matrix Metalloproteinase 1 in Regulating Fibroblast Proliferation in Hypertrophic Scars

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Published in 2021 at "Aesthetic Plastic Surgery"

DOI: 10.1007/s00266-021-02331-2

Abstract: To the Editor, We have read the recent article by Zhang et al. [1] on investigating the value of miR-222 in hypertrophic scars (HS). In this study, the authors concluded that the overexpression of miR-222… read more here.

Keywords: mir 222; hypertrophic scars; fibroblast proliferation; group ... See more keywords

The Effect of Fibronectin-Immobilized Microgrooved Titanium Substrata on Cell Proliferation and Expression of Genes and Proteins in Human Gingival Fibroblasts

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Published in 2018 at "Tissue Engineering and Regenerative Medicine"

DOI: 10.1007/s13770-018-0153-7

Abstract: Background:We aimed to determine the effect of fibronectin (FN)-immobilized microgrooved titanium (Ti) on human gingival fibroblast proliferation, gene expression and protein expression.Methods:Photolithography was used to fabricate the microgrooved Ti, and amine funtionalization (silanization) was used… read more here.

Keywords: cell proliferation; fibroblast proliferation; proliferation; effect ... See more keywords

Hypoxia induces pulmonary fibroblast proliferation through NFAT signaling

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Published in 2018 at "Scientific Reports"

DOI: 10.1038/s41598-018-21073-x

Abstract: Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive and typically fatal lung disease with a very low survival rate. Excess accumulation of fibroblasts, myofibroblasts and extracellular matrix creates hypoxic conditions within the lungs, causing asphyxiation.… read more here.

Keywords: hif; fibroblast proliferation; proliferation; hypoxia induces ... See more keywords

Chitooligosaccharides promote diabetic wound healing by mediating fibroblast proliferation and migration

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Published in 2025 at "Scientific Reports"

DOI: 10.1038/s41598-024-84398-w

Abstract: Diabetic wounds are notoriously difficult to heal due to impaired cell repair mechanisms, reduced angiogenesis, and a heightened risk of infection. Fibroblasts play a vital role in wound healing by producing extracellular matrix (ECM) components… read more here.

Keywords: wound healing; fibroblast proliferation; proliferation migration; diabetic wound ... See more keywords

The Combination of Resveratrol and High-Fluence Light Emitting Diode-Red Light Produces Synergistic Photobotanical Inhibition of Fibroblast Proliferation and Collagen Synthesis: A Novel Treatment for Skin Fibrosis

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Published in 2017 at "Dermatologic Surgery"

DOI: 10.1097/dss.0000000000000921

Abstract: BACKGROUND Skin fibrosis is a debilitating condition that significantly impacts patient quality of life. Ultraviolet phototherapy is currently used to treat several diseases featuring skin fibrosis. High-fluence light-emitting diode–generated red light (HF-LED-RL) does not cause… read more here.

Keywords: fibroblast proliferation; proliferation; light; skin fibrosis ... See more keywords

Stimulatory Effect of Mammalian Exosomes on Intradermal Fibroblast Proliferation

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Published in 2025 at "Journal of Cosmetic Dermatology"

DOI: 10.1111/jocd.70027

Abstract: This study investigates the potential of extracellular vesicles (EVs) in skin regeneration and rejuvenation. EVs, nanoscale vesicles released by various cell types, play a crucial role in intercellular communication. read more here.

Keywords: intradermal fibroblast; effect mammalian; exosomes intradermal; stimulatory effect ... See more keywords

Hydrogen Sulfide Suppresses Skin Fibroblast Proliferation via Oxidative Stress Alleviation and Necroptosis Inhibition

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Published in 2022 at "Oxidative Medicine and Cellular Longevity"

DOI: 10.1155/2022/7434733

Abstract: Keloid is a common dermatofibrotic disease with excessive skin fibroblast proliferation. Hydrogen sulfide (H2S) as the third gasotransmitter improves fibrosis of various organs and tissues. Our study is aimed at investigating the effects and possible… read more here.

Keywords: proliferation via; via oxidative; skin fibroblast; fibroblast proliferation ... See more keywords

miR-21 enhances cardiac fibrotic remodeling and fibroblast proliferation via CADM1/STAT3 pathway

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Published in 2017 at "BMC Cardiovascular Disorders"

DOI: 10.1186/s12872-017-0520-7

Abstract: BackgroundCardiac fibrosis play a key role in the atrial fibrillation pathogenesis but the underlying potential molecular mechanism is still understood. However, potential mechanisms for miR-21 upregulation and its role in cardiac fibrosis remain unclear. The… read more here.

Keywords: cardiac fibrotic; fibroblast proliferation; mir; proliferation ... See more keywords

The inhibition of human lung fibroblast proliferation and differentiation by Gs-coupled receptors is not predicted by the magnitude of cAMP response

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Published in 2018 at "Respiratory Research"

DOI: 10.1186/s12931-018-0759-2

Abstract: BackgroundIdiopathic pulmonary fibrosis (IPF) is a chronic and progressive fibrotic lung disease for which there is no cure. Current therapeutics are only able to slow disease progression, therefore there is a need to explore alternative,… read more here.

Keywords: camp response; proliferation differentiation; fibroblast proliferation; camp ... See more keywords

Overexpression of miR-340-5p inhibits skin fibroblast proliferation by targeting Kruppel-like factor 2.

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Published in 2019 at "Current pharmaceutical biotechnology"

DOI: 10.2174/1389201020666190725112304

Abstract: OBJECTIVE MicroRNA (miR)-340-5p has been identified to play a key role in several cancers. However, the function of miR-340-5p in skin fibroblasts remains largely unknown. METHOD Gain of function was used by infecting the normal… read more here.

Keywords: overexpression; ontology; skin fibroblast; fibroblast proliferation ... See more keywords

Long Noncoding RNA FENDRR Inhibits Lung Fibroblast Proliferation via a Reduction of β-Catenin

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Published in 2021 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms22168536

Abstract: Idiopathic Pulmonary Fibrosis (IPF) is a chronic, progressive, and usually lethal lung disease and it has been widely accepted that fibroblast proliferation is one of the key characteristics of IPF. Long noncoding RNAs (lncRNAs) play… read more here.

Keywords: long noncoding; reduction catenin; fibroblast proliferation; proliferation ... See more keywords