Articles with "fibroblast senescence" as a keyword



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MMP1 drives tumor progression in large cell carcinoma of the lung through fibroblast senescence.

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Published in 2021 at "Cancer letters"

DOI: 10.1016/j.canlet.2021.01.028

Abstract: Large cell carcinoma (LCC) is a rare and aggressive lung cancer subtype with poor prognosis and no targeted therapies. Tumor-associated fibroblasts (TAFs) derived from LCC tumors exhibit premature senescence, and coculture of pulmonary fibroblasts with… read more here.

Keywords: fibroblast senescence; cell carcinoma; senescence; large cell ... See more keywords
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Baicalein attenuates bleomycin-induced lung fibroblast senescence and lung fibrosis through restoration of Sirt3 expression

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Published in 2023 at "Pharmaceutical Biology"

DOI: 10.1080/13880209.2022.2160767

Abstract: Abstract Context Fibroblast senescence was reported to contribute to the pathological development of idiopathic pulmonary fibrosis (IPF), and baicalein is reported to attenuate IPF. Objective This study explores whether baicalein attenuates lung fibrosis by regulating… read more here.

Keywords: lung; fibroblast senescence; baicalein; lung fibrosis ... See more keywords
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Molecular Mechanisms of Malignant Transformation of Oral Submucous Fibrosis by Different Betel Quid Constituents—Does Fibroblast Senescence Play a Role?

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Published in 2022 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms23031637

Abstract: Betel quid (BQ) is a package of mixed constituents that is chewed by more than 600 million people worldwide, particularly in Asia. The formulation of BQ depends on a variety of factors but typically includes… read more here.

Keywords: oral submucous; submucous fibrosis; fibroblast senescence; betel ... See more keywords
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Oxygen–Glucose Deprivation Promoted Fibroblast Senescence and Collagen Expression via IL11

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Published in 2022 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms232012090

Abstract: Cell senescence is one of the most important forms of injury induced by cardiovascular and other ischemic diseases. Fibroblasts are important participants in tissue repair after ischemic injury and the main source of IL11 secretion.… read more here.

Keywords: expression; fibroblast senescence; senescence; senescence collagen ... See more keywords