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   Articles with "fibroblasts derived" as a keyword



Fibroblasts derived from oesophageal adenocarcinoma differ in DNA methylation profile from normal oesophageal fibroblasts

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recommendations! Published in 2017 at "Scientific Reports"

DOI: 10.1038/s41598-017-03501-6

Abstract: Oesophageal adenocarcinoma (OAC) is increasing in incidence and has a poor prognosis. Tumour derived fibroblasts (TDFs) differ functionally from normal fibroblasts (NDFs), and play a pivotal role in cancer. Many of the differences persist through… read more here.

Keywords: methylation; normal oesophageal; oesophageal adenocarcinoma; fibroblasts derived ... See more keywords

In vitro study of polydopamine nanoparticles as protective antioxidant agents in fibroblasts derived from ARSACS patients.

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recommendations! Published in 2022 at "Biomaterials science"

DOI: 10.1039/d2bm00729k

Abstract: Reactive oxygen species (ROS) are active molecules involved in several biological functions. When the production of ROS is not counterbalanced by the action of protective antioxidant mechanisms present in living organisms, a condition of oxidative… read more here.

Keywords: fibroblasts derived; arsacs patients; protective antioxidant; derived arsacs ... See more keywords

Genome‐wide profiling reveals pervasive transcriptional alterations in fibroblasts derived from lesional skin in vitiligo including a reduced potential to proliferate

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recommendations! Published in 2022 at "Experimental Dermatology"

DOI: 10.1111/exd.14702

Abstract: Fibroblasts interact with keratinocytes and melanocytes to maintain skin homeostasis. However, the impact of selective melanocyte loss on the transcriptome of fibroblasts is not fully understood. Thus, we sought to understand the genome‐wide transcriptome of… read more here.

Keywords: pervasive transcriptional; transcriptional alterations; skin; genome wide ... See more keywords

Rapamycin Inhibits the Growth and Collagen Production of Fibroblasts Derived from Human Urethral Scar Tissue

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recommendations! Published in 2018 at "BioMed Research International"

DOI: 10.1155/2018/7851327

Abstract: Rapamycin can inhibit fibroblast proliferation, collagen accumulation, and urethral stricture in rabbits. Transforming growth factor-beta-1 (TGF-β1) signaling, with downstream recruitment of Smad2, is known to promote fibrosis. This in vitro study examined the effects of… read more here.

Keywords: collagen; fibroblasts derived; growth; rapamycin ... See more keywords

Uptake-Dependent and -Independent Effects of Fibroblasts-Derived Extracellular Vesicles on Bone Marrow Endothelial Cells from Patients with Multiple Myeloma: Therapeutic and Clinical Implications

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recommendations! Published in 2023 at "Biomedicines"

DOI: 10.3390/biomedicines11051400

Abstract: Extracellular vesicles (EVs) have emerged as important players in cell-to-cell communication within the bone marrow (BM) of multiple myeloma (MM) patients, where they mediate several tumor-associated processes. Here, we investigate the contribution of fibroblasts-derived EVs… read more here.

Keywords: extracellular vesicles; endothelial cells; bone marrow; fibroblasts derived ... See more keywords