TIMP-1 is upregulated, but not essential in hepatic fibrogenesis and carcinogenesis in mice
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DOI: 10.1038/s41598-017-00671-1
Abstract: Tissue inhibitor of metalloproteinases-1 (TIMP-1) is upregulated during hepatic fibrogenesis and considered to promote fibrosis in the injured liver by inhibition of matrix metalloproteases (MMP) and degradation of extracellular matrix. Moreover, TIMP-1 displays anti-apoptotic properties,… read more here.
Keywords: fibrogenesis carcinogenesis; fibrogenesis; hepatic fibrogenesis; timp ... See more keywords