Technetium labeled doxorubicin loaded silk fibroin nanoparticles: Optimization, characterization and in vitro evaluation
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Drug Delivery Science and Technology"
DOI: 10.1016/j.jddst.2020.101539
Abstract: Abstract The aim of the present research work was to design Tween-80 coated silk fibroin nanoparticles of doxorubicin (DOX) and it's radiolabeling with Technetium-99Â m (99mTc). Radiolabeling could be used as a tool to analyze the… read more here.
Keywords: times higher; silk fibroin; fibroin nanoparticles; loaded silk ... See more keywords
Sericin and fibroin nanoparticles—natural product for cancer therapy: a comprehensive review
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Polymeric Materials and Polymeric Biomaterials"
DOI: 10.1080/00914037.2019.1706515
Abstract: Abstract Silk, a natural compound of silkworm contains two proteins, sericin and fibroin. These proteins can be conjugated with other compounds to form silk-derived nanoparticles. The biomedical applications of silk-based nanoparticles for drug delivery and… read more here.
Keywords: nanoparticles natural; sericin fibroin; fibroin nanoparticles; review ... See more keywords
A Review for the Synthesis of Silk Fibroin Nanoparticles with Different Techniques and Their Ability to be Used for Drug Delivery
Sign Up to like & getrecommendations! Published in 2019 at "Current Analytical Chemistry"
DOI: 10.2174/1573411014666180917110650
Abstract: Silk fibroin is the main protein of silk, and it has recently been evaluated for drug delivery applications due to its excellent properties. Specifically, silk fibroin exhibits good biocompatibility, biodegradability and low immunogenicity. Fibroin nanoparticles… read more here.
Keywords: microscopy; fibroin nanoparticles; drug; silk fibroin ... See more keywords
Selective Encapsulation of the Polyphenols on Silk Fibroin Nanoparticles: Optimization Approaches
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24119327
Abstract: The present study proposes a method for designing small bioactive nanoparticles using silk fibroin as a carrier to deliver hydrophobic polyphenols. Quercetin and trans-resveratrol, widely distributed in vegetables and plants, are used here as model… read more here.
Keywords: polyphenols silk; selective encapsulation; encapsulation polyphenols; silk fibroin ... See more keywords
Improving Anticancer Therapy with Naringenin-Loaded Silk Fibroin Nanoparticles
Sign Up to like & getrecommendations! Published in 2020 at "Nanomaterials"
DOI: 10.3390/nano10040718
Abstract: Naringenin (NAR), a flavonoid present in a variety of fruits, vegetables and herbs, exhibits a wide range of pharmacological effects, including anticancer activity. Nevertheless, its application in cancer therapy is limited due to its low… read more here.
Keywords: fibroin nanoparticles; loaded silk; nar sfns; silk fibroin ... See more keywords
Production of Curcumin-Loaded Silk Fibroin Nanoparticles for Cancer Therapy
Sign Up to like & getrecommendations! Published in 2018 at "Nanomaterials"
DOI: 10.3390/nano8020126
Abstract: Curcumin, extracted from the rhizome of Curcuma longa, has been widely used in medicine for centuries due to its anti-inflammatory, anti-cancer, anti-oxidant and anti-microbial effects. However, its bioavailability during treatments is poor because of its… read more here.
Keywords: silk; silk fibroin; curcumin loaded; fibroin nanoparticles ... See more keywords
In Vitro Hemocompatibility and Genotoxicity Evaluation of Dual-Labeled [99mTc]Tc-FITC-Silk Fibroin Nanoparticles for Biomedical Applications
Sign Up to like & getrecommendations! Published in 2023 at "Pharmaceuticals"
DOI: 10.3390/ph16020248
Abstract: Nuclear imaging is a highly sensitive and noninvasive imaging technique that has become essential for medical diagnosis. The use of radiolabeled nanomaterials capable of acting as imaging probes has shown rapid development in recent years… read more here.
Keywords: evaluation; silk fibroin; 99mtc fitc; hemocompatibility genotoxicity ... See more keywords
The Effect of Sterilization on the Characteristics of Silk Fibroin Nanoparticles
Sign Up to like & getrecommendations! Published in 2022 at "Polymers"
DOI: 10.3390/polym14030498
Abstract: In recent years, silk fibroin nanoparticles (SFNs) have been consolidated as drug delivery systems (DDSs) with multiple applications in personalized medicine. The design of a simple, inexpensive, and scalable preparation method is an objective pursued… read more here.
Keywords: sterilization sfns; effect; silk fibroin; sterilization ... See more keywords
Silk Fibroin Nanoparticles for Drug Delivery: Effect of Bovine Serum Albumin and Magnetic Nanoparticles Addition on Drug Encapsulation and Release
Sign Up to like & getrecommendations! Published in 2018 at "Separations"
DOI: 10.3390/separations5020025
Abstract: Silk fibroin nanoparticles were prepared in the present study based on phase separation between silk fibroin and polyvinyl alcohol. The drug encapsulation efficiency of the prepared nanoparticles was examined at a range of concentrations from… read more here.
Keywords: drug; drug encapsulation; silk fibroin; fibroin nanoparticles ... See more keywords