Guiding Fibroblast Activation Using an RGD-Mutated Heparin Binding II Fragment of Fibronectin for Gingival Titanium Integration.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202203307
Abstract: The formation of a biological seal around the neck of titanium (Ti) implants is critical for ensuring integration at the gingival site and for preventing bacterial colonization that may lead to periimplantitis. This process is… read more here.
Keywords: fibronectin; rgd; integration; heparin binding ... See more keywords
MMP7 cleaves remyelination‐impairing fibronectin aggregates and its expression is reduced in chronic multiple sclerosis lesions
Sign Up to like & getrecommendations! Published in 2018 at "Glia"
DOI: 10.1002/glia.23328
Abstract: Upon demyelination, transient expression of fibronectin precedes successful remyelination. However, in chronic demyelination observed in multiple sclerosis (MS), aggregates of fibronectin persist and contribute to remyelination failure. Accordingly, removing fibronectin (aggregates) would constitute an effective… read more here.
Keywords: remyelination; fibronectin; mmp7 cleaves; multiple sclerosis ... See more keywords
An O‐Glycosylation of Fibronectin Mediates Hepatic Osteodystrophy Through α4β1 Integrin
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Bone and Mineral Research"
DOI: 10.1002/jbmr.2916
Abstract: Patients with cholestatic liver disease experience increased fracture risk. Higher circulating levels of a fibronectin isoform called oncofetal fibronectin (oFN) were detected in a subset of such patients. Administering this isoform to mice suppresses osteoblast… read more here.
Keywords: hepatic osteodystrophy; fibronectin; integrin; glycosylation ... See more keywords
Fibronectin stimulates the osteogenic differentiation of murine embryonic stem cells
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Tissue Engineering and Regenerative Medicine"
DOI: 10.1002/term.2090
Abstract: Conditioned medium from human hepatocarcinoma cells (HepG2‐CM) has been shown to stimulate the osteogenic/chondrogenic differentiation of murine embryonic stem cells (mESCs). HepG2‐CM is considered to contain visceral endoderm (VE)‐like signals and attempts have recently been… read more here.
Keywords: murine embryonic; fibronectin; differentiation; osteogenic differentiation ... See more keywords
Functional Analysis of a Fibronectin Binding Protein of Streptococcus parasanguinis FW213
Sign Up to like & getrecommendations! Published in 2020 at "Current Microbiology"
DOI: 10.1007/s00284-020-02152-7
Abstract: Streptococcus parasanguinis is a primary colonizer of dental plaque and an opportunistic pathogen for subacute endocarditis. A putative fibronectin binding protein (Spaf_1409) that lacks both an N-terminal signal peptide and a C-terminal cell wall-anchoring motif… read more here.
Keywords: spaf 1409; parasanguinis fw213; fibronectin; streptococcus parasanguinis ... See more keywords
Differential Regulation of Neurite Outgrowth and Growth Cone Morphology by 3D Fibronectin and Fibronectin-Collagen Extracellular Matrices.
Sign Up to like & getrecommendations! Published in 2021 at "Molecular neurobiology"
DOI: 10.1007/s12035-021-02637-x
Abstract: The extracellular matrix (ECM) plays a critical role in development, homeostasis, and regeneration of tissue structures and functions. Cell interactions with the ECM are dynamic and cells respond to ECM remodeling by changes in morphology… read more here.
Keywords: fibronectin; growth cone; matrix; growth ... See more keywords
Fibronectin in development and wound healing.
Sign Up to like & getrecommendations! Published in 2020 at "Advanced drug delivery reviews"
DOI: 10.1016/j.addr.2020.09.005
Abstract: Fibronectin structure and composition regulate contextual cell signaling. Recent advances have been made in understanding fibronectin and its role in tissue organization and repair. This review outlines fibronectin splice variants and their functions, evaluates potential… read more here.
Keywords: wound healing; development wound; fibronectin; fibronectin development ... See more keywords
Effect of Endoplasmic Reticulum Stress and Autophagy in the Regulation of Post-infarct Cardiac Repair.
Sign Up to like & getrecommendations! Published in 2018 at "Archives of medical research"
DOI: 10.1016/j.arcmed.2018.07.001
Abstract: BACKGROUND Acute myocardial infarction (AMI) is reported to be accompanied by endoplasmic reticulum (ER) stress and autophagy induction. Nevertheless, the roles of ER stress and autophagy in post-infarct reparative fibrosis remain to be elucidated. AIM… read more here.
Keywords: stress autophagy; endoplasmic reticulum; fibronectin; stress ... See more keywords
Bi-specific tenascin-C and fibronectin targeted peptide for solid tumor delivery.
Sign Up to like & getrecommendations! Published in 2019 at "Biomaterials"
DOI: 10.1016/j.biomaterials.2019.119373
Abstract: Oncofetal fibronectin (FN-EDB) and tenascin-C C domain (TNC-C) are nearly absent in extracellular matrix of normal adult tissues but upregulated in malignant tissues. Both FN-EDB and TNC-C are developed as targets of antibody-based therapies. Here… read more here.
Keywords: delivery; fibronectin; fibronectin targeted; specific tenascin ... See more keywords
Local Arrangement of Fibronectin by Myofibroblasts Governs Peripheral Nuclear Positioning in Muscle Cells
Sign Up to like & getrecommendations! Published in 2018 at "Developmental Cell"
DOI: 10.1016/j.devcel.2018.05.031
Abstract: Summary Skeletal muscle cells (myofibers) are rod-shaped multinucleated cells surrounded by an extracellular matrix (ECM) basal lamina. In contrast to other cell types, nuclei in myofibers are positioned just below the plasma membrane at the… read more here.
Keywords: peripheral nuclear; fibronectin; muscle cells; local arrangement ... See more keywords
Thrombospondin-2 is up-regulated by TGFβ2 and increases fibronectin expression in human trabecular meshwork cells.
Sign Up to like & getrecommendations! Published in 2019 at "Experimental eye research"
DOI: 10.1016/j.exer.2019.107820
Abstract: Elevated intraocular pressure (IOP) is a major risk factor for the development of primary open-angle glaucoma (POAG). This is from an increased aqueous humor (AH) outflow resistance through the trabecular meshwork (TM). The pathogenic mechanisms… read more here.
Keywords: trabecular meshwork; fibronectin; pathogenesis poag; ecm ... See more keywords