Plasmin reduces fibronectin deposition by mesangial cells in a protease-activated receptor-1 independent manner
Sign Up to like & getrecommendations! Published in 2017 at "Biochemistry and Biophysics Reports"
DOI: 10.1016/j.bbrep.2017.03.009
Abstract: Background Protease-activated receptor-1 (PAR-1) potentiates diabetic nephropathy (DN) as evident from reduced kidney injury in diabetic PAR-1 deficient mice. Although thrombin is the prototypical PAR-1 agonist, anticoagulant treatment does not limit DN in experimental animal… read more here.
Keywords: fibronectin deposition; protease; par agonist; par ... See more keywords
Astrocyte-derived tissue Transglutaminase affects fibronectin deposition, but not aggregation, during cuprizone-induced demyelination
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DOI: 10.1038/srep40995
Abstract: Astrogliosis as seen in Multiple Sclerosis (MS) develops into astroglial scarring, which is beneficial because it seals off the site of central nervous system (CNS) damage. However, astroglial scarring also forms an obstacle that inhibits… read more here.
Keywords: demyelination; cuprizone; deposition aggregation; deposition ... See more keywords