MiR-33 promotes myocardial fibrosis by inhibiting MMP16 and stimulating p38 MAPK signaling
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DOI: 10.18632/oncotarget.25173
Abstract: Myocardial fibrosis occurs in the late stages of many cardiovascular diseases, and appears to be stimulated by various microRNAs (miRNAs). We previously found that miR-33 may stimulate cardiac remodeling. Here, we examined the involvement of… read more here.
Keywords: fibrosis; mmp16; myocardial fibrosis; fibrosis inhibiting ... See more keywords
Fluorofenidone Alleviates Renal Fibrosis by Inhibiting Necroptosis Through RIPK3/MLKL Pathway
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2020.534775
Abstract: Cell death and sterile inflammation are major mechanisms of renal fibrosis, which eventually develop into end-stage renal disease. “Necroptosis” is a type of caspase-independent regulated cell death, and sterile inflammatory response caused by tissue injury… read more here.
Keywords: fibrosis; ripk3 mlkl; inhibiting necroptosis; fibrosis inhibiting ... See more keywords