The clinical relevance of lymphocyte to monocyte ratio in patients with Idiopathic Pulmonary Fibrosis (IPF).
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DOI: 10.1016/j.rmed.2021.106686
Abstract: Disease course in Idiopathic Pulmonary Fibrosis (IPF) is highly heterogeneous and markers of disease progression would be helpful. Blood leukocyte count has been studied in cancer patients and a reduced lymphocyte to monocyte ratio (LMR)… read more here.
Keywords: diagnosed ipf; ipf; pulmonary fibrosis; idiopathic pulmonary ... See more keywords
Acute exacerbations of idiopathic pulmonary fibrosis (AE-IPF): an overview of current and future therapeutic strategies
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DOI: 10.1080/17476348.2020.1724096
Abstract: ABSTRACT Introduction: Idiopathic pulmonary fibrosis (IPF), the most common of the idiopathic interstitial pneumonias, is a disease with a poor prognosis, and a highly heterogeneous and unpredictable clinical course. While most patients experience a relatively… read more here.
Keywords: acute exacerbations; idiopathic pulmonary; fibrosis ipf; therapeutic strategies ... See more keywords
Clinical, radiologic, and physiologic features of idiopathic pulmonary fibrosis (IPF) with and without emphysema
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DOI: 10.1080/17476348.2022.2093717
Abstract: ABSTRACT Background Idiopathic pulmonary fibrosis (IPF) can combine with emphysema, a condition termed as IPF with emphysema (IPFE). We compared the clinical, radiologic, and physiologic features of IPF and IPFE. Research design and methods Newly… read more here.
Keywords: fibrosis ipf; ipf; idiopathic pulmonary; pulmonary fibrosis ... See more keywords
Chronic Expression of a Clinical SFTPC Mutation Causes Murine Lung Fibrosis with IPF Features.
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DOI: 10.1165/rcmb.2022-0203ma
Abstract: Idiopathic Pulmonary Fibrosis (IPF) is a chronic progressive fibrotic interstitial lung disease (ILD). A barrier to developing more effective therapies for IPF is the dearth of preclinical models that recapitulate the early pathobiology of this… read more here.
Keywords: fibrosis ipf; ipf; lung; sftpc mutation ... See more keywords
Antibody-mediated depletion of CCR10+EphA3+ cells ameliorates fibrosis in IPF
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DOI: 10.1172/jci.insight.141061
Abstract: Idiopathic pulmonary fibrosis (IPF) is characterized by aberrant repair that diminishes lung function via mechanisms that remain poorly understood. CC chemokine receptor (CCR10) and its ligand CCL28 were both elevated in IPF compared with normal… read more here.
Keywords: epha3 cells; fibrosis; fibrosis ipf; ccr10 cells ... See more keywords
TGF-β pathway activation by idiopathic pulmonary fibrosis (IPF) fibroblast derived soluble factors is mediated by IL-6 trans-signaling
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DOI: 10.1186/s12931-020-1319-0
Abstract: Background Idiopathic pulmonary fibrosis (IPF) is a chronic and ultimately fatal disease characterized by a progressive decline in lung function. Fibrotic diseases, such as IPF, are characterized by uncontrolled activation of fibroblasts. Since the microenvironment… read more here.
Keywords: idiopathic pulmonary; fibrosis ipf; ipf hlf; pulmonary fibrosis ... See more keywords