Deletion of Protein Kinase D3 Promotes Liver Fibrosis in Mice
Sign Up to like & getrecommendations! Published in 2020 at "Hepatology"
DOI: 10.1002/hep.31176
Abstract: Liver fibrosis (LF) is a central pathological process that occurs in most types of chronic liver diseases. Advanced LF causes cirrhosis, hepatocellular carcinoma, and liver failure. However, the exact molecular mechanisms underlying the initiation and… read more here.
Keywords: kinase promotes; liver fibrosis; promotes liver; deletion protein ... See more keywords
Interleukin-37 Attenuates Bleomycin-Induced Pulmonary Inflammation and Fibrosis in Mice
Sign Up to like & getrecommendations! Published in 2018 at "Inflammation"
DOI: 10.1007/s10753-018-0820-9
Abstract: Pulmonary fibrosis is a disease with chronic inflammation and excessive collagen deposition for which there is no effective treatments. Interleukin (IL)-37 is a newly identified anti-inflammatory cytokine but its role in pulmonary fibrosis remains unclear.… read more here.
Keywords: bleomycin induced; fibrosis; induced pulmonary; fibrosis mice ... See more keywords
Manual Mobilization of Subcutaneous Fibrosis in Mice
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Manipulative and Physiological Therapeutics"
DOI: 10.1016/j.jmpt.2017.10.011
Abstract: Objective: The aim of this study was to induce the remodeling of subcutaneous fibrosis in mice by the manual mobilization of skin and subcutaneous tissue. Methods: Seven days after the induction of subcutaneous fibrosis, mice… read more here.
Keywords: manual mobilization; fibrosis mice; subcutaneous fibrosis; mobilization ... See more keywords
Dietary fiber regulates intestinal flora and suppresses liver and systemic inflammation to alleviate liver fibrosis in mice.
Sign Up to like & getrecommendations! Published in 2020 at "Nutrition"
DOI: 10.1016/j.nut.2020.110959
Abstract: OBJECTIVES Liver fibrosis is a common pathologic process related to chronic liver disease. However, there are currently no effective methods to reverse liver fibrosis. Chronic liver disease is typically associated with a major imbalance in… read more here.
Keywords: fibrosis mice; dietary fiber; intestinal flora; liver fibrosis ... See more keywords
Antifibrotic effects of crocin on thioacetamide-induced liver fibrosis in mice
Sign Up to like & getrecommendations! Published in 2018 at "Saudi Journal of Biological Sciences"
DOI: 10.1016/j.sjbs.2016.10.007
Abstract: Liver fibrosis is a major health concern that results in significant morbidity and mortality. Up-to-date, there is no standard treatment for fibrosis because of its complex pathogenesis. Crocin is one of the main nutraceuticals isolated… read more here.
Keywords: fibrosis; liver fibrosis; fibrosis mice; expression ... See more keywords
P1196AN INIHIBITOR OF KRUPPEL-LIKE FACTOR 5 SUPPRESSES PERITONEAL FIBROSIS IN MICE
Sign Up to like & getrecommendations! Published in 2020 at "Nephrology Dialysis Transplantation"
DOI: 10.1093/ndt/gfaa142.p1196
Abstract: We presented previously that Am80, a synthetic retinoic acid receptor α specific agonist, inhibited the expression of Krüppel-like transcription factor 5 (KLF5) and reduced peritoneal fibrosis in mice. Now, we examined further detail about the… read more here.
Keywords: peritoneal fibrosis; fibrosis; fibrosis mice; klf5 ... See more keywords
Iguratimod ameliorates bleomycin‐induced alveolar inflammation and pulmonary fibrosis in mice by suppressing expression of matrix metalloproteinase‐9
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Rheumatic Diseases"
DOI: 10.1111/1756-185x.13463
Abstract: To investigate the potential therapeutic efficacy of iguratimod (IGU) on bleomycin (BLM)‐induced pulmonary fibrosis in mice. read more here.
Keywords: bleomycin induced; ameliorates bleomycin; pulmonary fibrosis; fibrosis mice ... See more keywords
Blockade of platelet-derived growth factor receptor-β, not receptor-α ameliorates bleomycin-induced pulmonary fibrosis in mice
Sign Up to like & getrecommendations! Published in 2018 at "PLoS ONE"
DOI: 10.1371/journal.pone.0209786
Abstract: Platelet-derived growth factor (PDGF) has been implicated in the pathogenesis of pulmonary fibrosis. Nintedanib, a multi-kinase inhibitor that targets several tyrosine kinases, including PDGF receptor (PDGFR), was recently approved as an anti-fibrotic agent to reduce… read more here.
Keywords: fibrosis; induced pulmonary; fibrosis mice; pulmonary fibrosis ... See more keywords
Antifibrotic Mechanism of Cinobufagin in Bleomycin-Induced Pulmonary Fibrosis in Mice
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2019.01021
Abstract: Idiopathic pulmonary fibrosis (IPF) is a progressive and usually fatal lung disease that is characterized by fibroblast proliferation and extracellular matrix remodeling, which result in irreversible distortion of the lung’s architecture and the formation of… read more here.
Keywords: bleomycin induced; fibrosis; induced pulmonary; cinobufagin ... See more keywords
Fenbendazole Attenuates Bleomycin-Induced Pulmonary Fibrosis in Mice via Suppression of Fibroblast-to-Myofibroblast Differentiation
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms232214088
Abstract: Idiopathic pulmonary fibrosis (IPF) is a chronic, progressive, and fatal interstitial lung disease with unknown etiology. Despite substantial progress in understanding the pathogenesis of pulmonary fibrosis and drug development, there is still no cure for… read more here.
Keywords: myofibroblast differentiation; fibrosis mice; bleomycin induced; fibroblast myofibroblast ... See more keywords
Protective effects of Foeniculum vulgare root bark extract against carbon tetrachloride-induced hepatic fibrosis in mice
Sign Up to like & getrecommendations! Published in 2017 at "World Journal of Gastroenterology"
DOI: 10.3748/wjg.v23.i31.5722
Abstract: AIM To investigate the protective effects of Foeniculum vulgare root bark (FVRB), a traditional Uyghur medicine, against carbon tetrachloride (CCl4)-induced hepatic fibrosis in mice. METHODS Mice were randomly divided into eight groups (n = 20… read more here.
Keywords: fibrosis; fibrosis mice; hepatic fibrosis; mice ... See more keywords