Autophagy affects hepatic fibrosis progression by regulating macrophage polarization and exosome secretion.
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DOI: 10.1002/tox.23795
Abstract: BACKGROUND In this study, the role of autophagy in hepatic fibrosis and its effects on macrophage polarization and exosomes (EVs) were verified by establishing hepatic fibrosis model and co-culture model, providing evidence for treatment. METHODS… read more here.
Keywords: macrophage polarization; fibrosis; fibrosis model; hepatic fibrosis ... See more keywords
Novel liver fibrosis model in Macaca fascicularis induced by thioacetamide
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DOI: 10.1038/s41598-020-58739-4
Abstract: Although transplantation is the only definitive treatment for liver cirrhosis, there remains a shortage of donors, necessitating that novel treatments be developed. We aimed to establish a liver fibrosis model in Macaca fascicularis that can… read more here.
Keywords: fibrosis model; model macaca; fibrosis; macaca fascicularis ... See more keywords
25(OH) D3 alleviate liver NK cytotoxicity in acute but not in chronic fibrosis model of BALB/c mice due to modulations in vitamin D receptor
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DOI: 10.1186/s12876-020-01248-5
Abstract: Background Low 25-Hydroxy-vitamin-D; “25(OH)-D3” serum and vitamin D receptor (VDR) levels were recently correlated to advanced fibrosis. However, VDR mechanism in liver fibrosis modulations is not well understood. In this study, we aimed to evaluate… read more here.
Keywords: fibrosis model; fibrosis; vitamin receptor; due modulations ... See more keywords