Role of Toll-like Receptor 4 Expressed by Fibroblasts in Allograft Fibrosis in Mouse Orthotopic Tracheal Transplantation.
Sign Up to like & getrecommendations! Published in 2018 at "Transplantation proceedings"
DOI: 10.1016/j.transproceed.2018.06.023
Abstract: Development of chronic lung allograft dysfunction involves various alloimmune-independent insults including those mediated by Toll-like receptor (TLR) signaling, which is known to activate alloimmune responses. We hypothesized that TLR signaling may also contribute to the… read more here.
Keywords: toll like; mouse orthotopic; like receptor; orthotopic tracheal ... See more keywords
Sialidase inhibitors attenuate pulmonary fibrosis in a mouse model
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DOI: 10.1038/s41598-017-15198-8
Abstract: Fibrosis involves increasing amounts of scar tissue appearing in a tissue, but what drives this is unclear. In fibrotic lesions in human and mouse lungs, we found extensive desialylation of glycoconjugates, and upregulation of sialidases.… read more here.
Keywords: fibrosis; sialidase inhibitors; sialidase; pulmonary fibrosis ... See more keywords