Interleukin 2 Promotes Hepatic Regulatory T Cell Responses and Protects From Biliary Fibrosis in Murine Sclerosing Cholangitis
Sign Up to like & getrecommendations! Published in 2018 at "Hepatology"
DOI: 10.1002/hep.30061
Abstract: In the multidrug resistance protein 2 (Mdr2)‐/‐ mouse model, low phospholipid bile instigates biliary epithelial injury, sterile inflammation, and fibrosis, thereby recapitulating disease mechanisms implicated in biliary atresia (BA) and primary sclerosing cholangitis. We hypothesize… read more here.
Keywords: fibrosis murine; cd8 lymphocytes; cd8; fibrosis ... See more keywords
Protective Effects of Carnosol on Renal Interstitial Fibrosis in a Murine Model of Unilateral Ureteral Obstruction
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DOI: 10.3390/antiox11122341
Abstract: Renal fibrosis is a common feature of chronic kidney disease and is a promising therapeutic target. However, there is still limited treatment for renal fibrosis, so the development of new anti-fibrotic agents is urgently needed.… read more here.
Keywords: model unilateral; unilateral ureteral; model; fibrosis ... See more keywords
Continuous NPWT Regulates Fibrosis in Murine Diabetic Wound Healing
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DOI: 10.3390/pharmaceutics14102125
Abstract: Scarring is associated with significant morbidity. The mechanical signaling factor yes-associated protein (YAP) has been linked to Engrailed-1 (En1)-lineage positive fibroblasts (EPFs), a pro-scarring fibroblast lineage, establishing a connection between mechanotransduction and fibrosis. In this… read more here.
Keywords: wound; npwt regulates; continuous npwt; regulates fibrosis ... See more keywords