Exosomes and MicroRNA‐223 at the Intersection of Inflammation and Fibrosis in NAFLD
Sign Up to like & getrecommendations! Published in 2021 at "Hepatology"
DOI: 10.1002/hep.31805
Abstract: Nonalcoholic fatty liver and nonalcoholic steatohepatitis (NASH) are the most common causes of liver disease. Progression of nonalcoholic fatty liver disease (NAFLD) to NASH is mediated by multiple signals that include activation of inflammatory cells,… read more here.
Keywords: inflammation fibrosis; intersection inflammation; exosomes microrna; fibrosis nafld ... See more keywords
PNPLA3 rs738409 and risk of fibrosis in NAFLD: Exploring mediation pathways through intermediate histological features
Sign Up to like & getrecommendations! Published in 2022 at "Hepatology"
DOI: 10.1002/hep.32491
Abstract: It is unclear whether rs738409 (p.I148M) missense variant in patatin‐like phospholipase domain‐containing 3 rs738409 promotes fibrosis development by triggering specific fibrogenic pathways or by creating an unfavorable microenvironment by promoting steatosis, inflammation, and ultimately fibrosis.… read more here.
Keywords: pnpla3 rs738409; fibrosis nafld; rs738409 risk; risk fibrosis ... See more keywords