Upregulation of neurotrophins and transforming growth factor‐β expression in the bladder may lead to nerve hyperplasia and fibrosis in patients with severe ketamine‐associated cystitis
Sign Up to like & getrecommendations! Published in 2019 at "Neurourology and Urodynamics"
DOI: 10.1002/nau.24139
Abstract: To investigate the mechanism of bladder nerve hyperplasia and fibrosis in the patients with ketamine‐associated cystitis (KC). read more here.
Keywords: associated cystitis; ketamine associated; hyperplasia fibrosis; bladder ... See more keywords
Prevalence of hearing and vestibular loss in cystic fibrosis patients exposed to aminoglycosides
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DOI: 10.1002/ppul.23763
Abstract: Cystic Fibrosis (CF) patients frequently use aminoglycosides (AGS) to treat CF exacerbation due to colonization with Pseudomonas aeruginosa. Although AGS can cause vestibular and auditory sensory losses that can negatively impact quality of life, little… read more here.
Keywords: cystic fibrosis; vestibular loss; fibrosis patients; prevalence ... See more keywords
Comparison of the predictive value of area under the curve versus maximum serum concentration of intravenous tobramycin in cystic fibrosis patients treated for an acute pulmonary exacerbation
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DOI: 10.1002/ppul.25569
Abstract: The primary objective of this study was to compare the therapeutic predictive value of area under the curve (AUC24) versus maximum concentration (Cmax) in cystic fibrosis (CF) patients receiving intravenous (IV) tobramycin for a Pseudomonas… read more here.
Keywords: cystic fibrosis; value area; fibrosis patients; area curve ... See more keywords
Pharmacist‐administered audiology screening for pediatric cystic fibrosis patients exposed to high‐dose aminoglycosides: A pilot study
Sign Up to like & getrecommendations! Published in 2022 at "Pediatric Pulmonology"
DOI: 10.1002/ppul.25946
Abstract: This pilot study successfully implemented a standardized protocol for tablet‐based ototoxicity screening in pediatric cystic fibrosis (CF) patients exposed to aminoglycosides. Further studies are needed to assess the impact of implementation in a larger number… read more here.
Keywords: fibrosis patients; pediatric cystic; screening pediatric; audiology ... See more keywords
Methotrexate does not increase the risk of liver fibrosis in patients with rheumatoid arthritis: assessment by ultrasound elastography (ARFI-MetRA study)
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DOI: 10.1007/s00296-021-04804-8
Abstract: Only limited data are available on the risk of liver fibrosis in patients with rheumatoid arthritis on long-term methotrexate treatment. To assess the risk of liver fibrosis in patients with rheumatoid arthritis treated with methotrexate,… read more here.
Keywords: fibrosis; arfi; liver fibrosis; risk liver ... See more keywords
Applicability of APRI and FIB-4 as a transition indicator of liver fibrosis in patients with chronic viral hepatitis
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DOI: 10.1007/s00535-021-01782-3
Abstract: The usefulness of APRI or FIB-4 is well established as a non-invasive liver fibrosis marker at a point of diagnosis in patients with chronic liver disease. However, their applicability for the monitoring of progression of… read more here.
Keywords: liver fibrosis; hepatitis; fibrosis patients; apri fib ... See more keywords
Phenotypic and genetic resistance traits of Pseudomonas aeruginosa strains infecting cystic fibrosis patients: A French cohort study.
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DOI: 10.1016/j.ijantimicag.2018.05.008
Abstract: Pseudomonas aeruginosa is responsible for chronic respiratory tract colonisation and acute exacerbations in cystic fibrosis (CF) patients. This Gram-negative bacterium often develops multidrug resistance, which represents a therapeutic challenge. The objective of this study was… read more here.
Keywords: cystic fibrosis; pseudomonas aeruginosa; study; fibrosis patients ... See more keywords
The first report on immunoglobulins A, E, G and M levels in cystic fibrosis patients in Saudi Arabia
Sign Up to like & getrecommendations! Published in 2020 at "Saudi Journal of Biological Sciences"
DOI: 10.1016/j.sjbs.2020.05.041
Abstract: Background Previous reports have shown that pulmonary and systemic hypergamma-globulinemia in CF patients is a reflection of chronic pulmonary infection. Infection with Pseudomonas aeruginosa is known to have major prognostic significance in patients CF. This… read more here.
Keywords: cystic fibrosis; immunoglobulins levels; fibrosis patients; first report ... See more keywords
Discovery of Novel Inhibitors of Uridine Diphosphate-N-Acetylenolpyruvylglucosamine Reductase (MurB) from Pseudomonas aeruginosa, an Opportunistic Infectious Agent Causing Death in Cystic Fibrosis Patients.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.1c01684
Abstract: Pseudomonas aeruginosa is of major concern for cystic fibrosis patients where this infection can be fatal. With the emergence of drug-resistant strains, there is an urgent need to develop novel antibiotics against P. aeruginosa. MurB… read more here.
Keywords: fibrosis patients; discovery novel; murb; pseudomonas aeruginosa ... See more keywords
Antimicrobial Peptides against Multidrug-Resistant Pseudomonas aeruginosa Biofilm from Cystic Fibrosis Patients
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Medicinal Chemistry"
DOI: 10.1021/acs.jmedchem.2c00270
Abstract: Lung infection is the leading cause of morbidity and mortality in cystic fibrosis (CF) patients and is mainly dominated by Pseudomonas aeruginosa. Treatment of CF-associated lung infections is problematic because the drugs are vulnerable to… read more here.
Keywords: fibrosis patients; pseudomonas aeruginosa; antimicrobial peptides; multidrug resistant ... See more keywords
Noninvasive assessment and risk factors of liver fibrosis in patients with thalassemia major using shear wave elastography
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DOI: 10.1080/10245332.2018.1540518
Abstract: ABSTRACT Objectives: This study aimed to estimate the prevalence of liver fibrosis and assess the risk factors for developing significant liver fibrosis in patients with Thalassemia Major (TM). Methods: All patients with TM over the… read more here.
Keywords: fibrosis; liver fibrosis; patients thalassemia; fibrosis patients ... See more keywords