Clinical Utility of an Increase in Magnetic Resonance Elastography in Predicting Fibrosis Progression in Nonalcoholic Fatty Liver Disease
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DOI: 10.1002/hep.30974
Abstract: Cross‐sectional studies have shown that magnetic resonance elastography (MRE) is accurate in the noninvasive detection of advanced fibrosis in nonalcoholic fatty liver disease (NAFLD). However, there are limited data on the longitudinal association between an… read more here.
Keywords: fibrosis; resonance elastography; increase; magnetic resonance ... See more keywords
Glycemic burden and the risk of adverse hepatic outcomes in patients with chronic hepatitis B with type 2 diabetes
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DOI: 10.1002/hep.32716
Abstract: Background and Aims: Type 2 diabetes (T2D) is common among patients with chronic hepatitis B infection (CHB) and has been associated with increased risk of carcinogenesis, including HCC. We investigated factors associated with HCC and… read more here.
Keywords: patients chb; hba1c; glycemic burden; fibrosis progression ... See more keywords
α2-antiplasmin positively regulates endothelial-to-mesenchymal transition and fibrosis progression in diabetic nephropathy.
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DOI: 10.1007/s11033-021-06859-z
Abstract: BACKGROUND Diabetic nephropathy (DN), is microvascular complication of diabetes causes to kidney dysfunction and renal fibrosis. It is known that hyperglycemia and advanced glycation end products (AGEs) produced by hyperglycemic condition induce myofibroblast differentiation and… read more here.
Keywords: fibrosis; condition; high glucose; diabetic nephropathy ... See more keywords
Temporal histopathological changes in biliary atresia: A perspective for rapid fibrosis progression.
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DOI: 10.1016/j.aohep.2020.09.007
Abstract: INTRODUCTION AND OBJECTIVES Biliary atresia (BA) is characterized by rapid progression of fibrosis with no definite causes. Histopathological findings have been extensively described, but very few studies have assessed temporal changes in BA. Understanding these… read more here.
Keywords: fibrosis; histopathological changes; fibrosis progression; biliary atresia ... See more keywords
Diverse effects of hepatic steatosis on fibrosis progression and functional cure in virologically quiescent chronic hepatitis B.
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DOI: 10.1016/j.jhep.2020.05.040
Abstract: BACKGROUND Concomitant non-alcoholic fatty liver disease is common in patients with chronic hepatitis B (CHB) infection, although its impact on liver-related outcomes remains controversial. We aimed to study the effect of hepatic steatosis on risk… read more here.
Keywords: hepatic steatosis; fibrosis; hepatitis; steatosis ... See more keywords
Mechanical communication in fibrosis progression.
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DOI: 10.1016/j.tcb.2021.10.002
Abstract: Mechanical hallmarks of fibrotic microenvironments are both outcomes and causes of fibrosis progression. Understanding how cells sense and transmit mechanical cues in the interplay with extracellular matrix (ECM) and hemodynamic forces is a significant challenge.… read more here.
Keywords: hemodynamics; mechanical communication; progression; fibrosis progression ... See more keywords
A variant in the MICA gene is associated with liver fibrosis progression in chronic hepatitis C through TGF-β1 dependent mechanisms
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DOI: 10.1038/s41598-018-35736-2
Abstract: Hepatocarcinogenesis is tightly linked to liver fibrosis. Recently, two GWAS variants, MICA rs2596542 and DEPDC5 rs1012068 were identified as being associated with the development of HCV-induced hepatocellular carcinoma (HCC) in Japanese patients. The role of… read more here.
Keywords: fibrosis; liver fibrosis; expression; chronic hepatitis ... See more keywords
Fibrosis Progression Rate in Biopsy-proven Nonalcoholic Fatty Liver Disease among People with Diabetes versus People without Diabetes: A Multicenter Study.
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DOI: 10.1053/j.gastro.2023.04.025
Abstract: BACKGROUND AND AIMS There are limited data regarding fibrosis progression in biopsy-proven nonalcoholic fatty liver disease (NAFLD), between people with type 2 diabetes mellitus (T2DM) versus people without T2DM. We assessed the time to fibrosis… read more here.
Keywords: versus people; people without; fibrosis progression; fibrosis ... See more keywords
The macrophage-associated microRNA-4715-3p / Gasdermin D axis potentially indicates fibrosis progression in nonalcoholic fatty liver disease: evidence from transcriptome and biological data
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DOI: 10.1080/21655979.2022.2072602
Abstract: ABSTRACT Nonalcoholic fatty liver disease (NAFLD) is highly possible to progress to cirrhosis, malignancy, and liver failure through fibrogenesis. The enormous potential of pathogenetic and therapeutic targets in NAFLD has been revealed. This study aimed… read more here.
Keywords: nonalcoholic fatty; fatty liver; progression; fibrosis progression ... See more keywords
FibroScan Predicts Liver Fibrosis Progression in Chronic HBV Infection Patients with No Clear Indication for Antiviral Therapy: A Retrospective Cohort Study
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DOI: 10.2147/idr.s402990
Abstract: Background and Aims Chronic hepatitis B virus (HBV) infection patients who do not fulfill the typical treatment indications should be followed up. This study aimed to evaluate the risk of liver fibrosis progression (LFP) and… read more here.
Keywords: liver fibrosis; hbv infection; infection patients; fibrosis progression ... See more keywords
Nomogram for Quantitatively Estimating the Risk of Fibrosis Progression in Type 2 Diabetic Patients With Nonalcoholic Fatty Liver Disease: A Pilot Study
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DOI: 10.3389/fendo.2022.917304
Abstract: Background Correct identification of the fibrosis progression risk is a critical step in the management of patients with type 2 diabetes mellitus (T2DM) and non-alcoholic fatty liver disease (NAFLD), because liver fibrosis, especially advanced liver… read more here.
Keywords: progression; risk fibrosis; fibrosis progression; fibrosis ... See more keywords