Muscle Fibrosis, NF- κ B, and TGF- β Are Differentially Altered in Two Models of Paralysis (Botox Versus Neurectomy)
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DOI: 10.1089/wound.2024.0045
Abstract: Objective : Volumetric muscle loss results in intramuscular axotomy, denervating muscle distal to the injury and leading to paralysis, denervation, and loss of muscle function. Once the nerve is damaged, paralyzed skeletal muscle will atrophy… read more here.
Keywords: paralysis; fibrosis; muscle fibrosis; muscle ... See more keywords
TGF-β Inhibitors for Therapeutic Management of Kidney Fibrosis
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DOI: 10.3390/ph15121485
Abstract: Kidney fibrosis is a common pathophysiological mechanism of chronic kidney disease (CKD) progression caused by several underlying kidney diseases. Among various contributors to kidney fibrosis, transforming growth factor-β1 (TGF-β1) is the major factor driving fibrosis.… read more here.
Keywords: kidney fibrosis; tgf inhibitors; kidney; management ... See more keywords