M2-like macrophages in the fibrotic liver protect mice against lethal insults through conferring apoptosis resistance to hepatocytes
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-11303-z
Abstract: Acute injury in the setting of liver fibrosis is an interesting and still unsettled issue. Most recently, several prominent studies have indicated the favourable effects of liver fibrosis against acute insults. Nevertheless, the underlying mechanisms… read more here.
Keywords: like macrophages; fibrotic liver; macrophages fibrotic; apoptosis resistance ... See more keywords
Aberrant regulation of autophagy disturbs fibrotic liver regeneration after partial hepatectomy
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.1030338
Abstract: Reports indicate that autophagy is essential for maintaining hepatocyte proliferative capacity during liver regeneration. However, the role of autophagy in fibrotic liver regeneration is incompletely elucidated. We investigated the deregulation of autophagic activities in liver… read more here.
Keywords: fibrotic liver; regeneration; liver regeneration; partial hepatectomy ... See more keywords
Extracellular vesicles: catching the light of intercellular communication in fibrotic liver diseases
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DOI: 10.7150/thno.77256
Abstract: The increasing prevalence of fibrotic liver diseases resulting from different etiologies has become a major global problem for public health. Fibrotic liver diseases represent a redundant accumulation of extracellular matrix, dysregulation of immune homeostasis and… read more here.
Keywords: fibrotic liver; liver; intercellular communication; extracellular vesicles ... See more keywords