Development and Course of Scars in the Comparison of Age-Related Macular Degeneration Treatments Trials.
Sign Up to like & getrecommendations! Published in 2018 at "Ophthalmology"
DOI: 10.1016/j.ophtha.2018.01.004
Abstract: PURPOSE To describe risk factors for scar formation and changes to fibrotic scar through 5 years in the Comparison of Age-related Macular Degeneration Treatments Trials (CATT). DESIGN Multicenter, prospective cohort study. PARTICIPANTS A total of… read more here.
Keywords: fibrotic scar; scar; scar formation; ahr versus ... See more keywords
FTY720 hinders IFN-γ-mediated fibrotic scar formation and facilitates neurological recovery after spinal cord injury.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of neurotrauma"
DOI: 10.1089/neu.2022.0387
Abstract: Following spinal cord injury (SCI), fibrotic scar inhibits axon regeneration and impairs neurological function recovery. It has been reported that T cell-derived IFN-γ plays a pivotal role in promoting fibrotic scarring in neurodegenerative disease. However,… read more here.
Keywords: fibrotic scar; fty720; scar formation; spinal cord ... See more keywords
Hepatic TREM2+ macrophages express matrix metalloproteinases to control fibrotic scar formation
Sign Up to like & getrecommendations! Published in 2022 at "Immunology and Cell Biology"
DOI: 10.1111/imcb.12616
Abstract: Liver cirrhosis is characterized by the extensive deposition of extracellular matrix such as fibril collagen, causing dysfunction and failure of the liver. Hepatic macrophages play pivotal roles in the transition from inflammatory to restorative properties… read more here.
Keywords: fibrotic scar; cell; trem2; scar ... See more keywords
Fibrotic Scar in Neurodegenerative Diseases
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2020.01394
Abstract: The process of uncontrolled internal scarring, called fibrosis, is now emerging as a pathological feature shared by both peripheral and central nervous system diseases. In the CNS, damaged neurons are not replaced by tissue regeneration,… read more here.
Keywords: fibrotic scar; scar; scar neurodegenerative; neurodegenerative diseases ... See more keywords