Tissue-engineered collagenous fibrous cap models to systematically elucidate atherosclerotic plaque rupture.
Sign Up to like & getrecommendations! Published in 2022 at "Scientific reports"
DOI: 10.1038/s41598-022-08425-4
Abstract: A significant amount of vascular thrombotic events are associated with rupture of the fibrous cap that overlie atherosclerotic plaques. Cap rupture is however difficult to predict due to the heterogenous composition of the plaque, unknown… read more here.
Keywords: tissue; plaque; fibrous cap; tissue engineered ... See more keywords
3284Quantification of macrophage presence and identification of thin-cap fibroatheroma by optical coherence tomography image: histopathological validation study
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DOI: 10.1093/eurheartj/ehz745.0055
Abstract: Intracoronary optical coherence tomography (OCT) is thought to be capable of identifying a vulnerable, rupture-prone plaque based on the presence of a thin-cap fibroatheroma (TCFA). Moreover, recent studies have reported that OCT may be able… read more here.
Keywords: fibrous cap; optical coherence; thin cap; coherence tomography ... See more keywords
Tribbles 3 deficiency promotes atherosclerotic fibrous cap thickening and macrophage-mediated extracellular matrix remodelling
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cardiovascular Medicine"
DOI: 10.3389/fcvm.2022.948461
Abstract: Tribbles 3 (TRIB3) modulates lipid and glucose metabolism, macrophage lipid uptake, with a gain-of-function variant associated with increased cardiovascular risk. Here we set out to examine the role of this pseudokinase in atherosclerotic plaque development.… read more here.
Keywords: extracellular matrix; fibrous cap; matrix remodelling; trib3 ... See more keywords
Increased Proximal Wall Shear Stress of Basilar Artery Plaques Associated with Ruptured Fibrous Cap
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DOI: 10.3390/brainsci12101397
Abstract: Plaque rupture of the basilar artery is one of the leading causes of posterior circulation stroke. The present study aimed to investigate the role of fluid dynamics in the ruptured fibrous cap of basilar artery… read more here.
Keywords: artery; fibrous cap; artery plaques; ruptured fibrous ... See more keywords