Anti-Ficolin-2 and Anti-Ficolin-3 Autoantibody Detection by ELISA.
Sign Up to like & getrecommendations! Published in 2021 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1016-9_12
Abstract: Ficolins are recognition proteins of the lectin pathway of the complement system and also play an important role in innate immunity and in the maintenance of tissue homeostasis. They deserve special attention in the context… read more here.
Keywords: autoantibody detection; ficolin autoantibody; ficolin anti; detection elisa ... See more keywords
Ficolin-2 triggers antitumor effect by activating macrophages and CD8+ T cells.
Sign Up to like & getrecommendations! Published in 2017 at "Clinical immunology"
DOI: 10.1016/j.clim.2017.08.012
Abstract: Ficolin-2 is an important serum complement lectin. Here, we describe novel findings indicating that serum ficolin-2 concentrations in multiple tumor patients are significantly lower than those in healthy donors. Administration of exogenous ficolin-2 or ficolin-A… read more here.
Keywords: antitumor effect; cells ficolin; ficolin triggers; cd8 cells ... See more keywords
Lectin pathway factors in patients suffering from juvenile idiopathic arthritis
Sign Up to like & getrecommendations! Published in 2017 at "Immunology and Cell Biology"
DOI: 10.1038/icb.2017.31
Abstract: Both complement activation and certain infections (including those with Yersinia sp.) may contribute to the pathogenesis of juvenile idiopathic arthritis (JIA). We investigated factors specific for the lectin pathway of complement: mannose‐binding lectin (MBL), ficolins… read more here.
Keywords: juvenile idiopathic; jia; lectin pathway; idiopathic arthritis ... See more keywords
Ficolin A derived from local macrophages and neutrophils protects against LPS-induced acute lung injury by activating complement.
Sign Up to like & getrecommendations! Published in 2020 at "Immunology and cell biology"
DOI: 10.1111/imcb.12344
Abstract: Ficolins are important and widely distributed pattern recognition molecules that can induce lectin complement pathway activation and initiate the innate immune response. Although ficolins can bind lipopolysaccharide (LPS) in vitro, the sources, dynamic changes and roles of local ficolins… read more here.
Keywords: lps induced; injury; lung injury; macrophages neutrophils ... See more keywords
Ficolin‐3 and MASP‐2 gene variants in Siberian arctic populations: Summarized evidence of selective pressure for the high frequency of lectin complement pathway deficiency
Sign Up to like & getrecommendations! Published in 2022 at "Scandinavian Journal of Immunology"
DOI: 10.1111/sji.13249
Abstract: Herewith, we provide novel original data about the prevalence of FCN3 rs532781899 and MASP2 rs72550870 variants among the newborns of aboriginal Siberian Arctic populations (Nenets and Dolgan‐Nganasans) and Russians of East Siberia. This novel data… read more here.
Keywords: lectin complement; prevalence; ficolin; gene ... See more keywords
Ficolin-1 in pediatric Plasmodium falciparum malaria and its possible role in parasite clearance and anemia
Sign Up to like & getrecommendations! Published in 2025 at "Infection and Immunity"
DOI: 10.1128/iai.00194-25
Abstract: ABSTRACT Plasmodium falciparum malaria causes significant disease, especially in young children. A successful immune response to P. falciparum is a major determinant of clinical outcome. The ficolins are a family of lectins that act as… read more here.
Keywords: falciparum; role; falciparum malaria; ficolin ... See more keywords
Ficolin-1 ameliorates pulmonary fibrosis via directly binding to TGF-β1
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Translational Medicine"
DOI: 10.1186/s12967-024-05894-1
Abstract: Ficolins were originally identified as proteins that bind to transforming growth factor-β1 (TGF-β1). They are capable of activating the complement system through lectin pathway for immune system protection. Ficolin-2 and 3 have been identified in… read more here.
Keywords: fibrosis; lung; tgf; ficolin ... See more keywords
Evaluation of Ficolin-3 deficiency as a risk factor in the development of rheumatic heart disease
Sign Up to like & getrecommendations! Published in 2025 at "BMC Research Notes"
DOI: 10.1186/s13104-025-07251-x
Abstract: Ficolin-3 is a crucial protein for the activation of the complement system. Previous work has indicated this protein may play a role in the pathogenesis of rheumatic heart disease (RHD), and it has been hypothesised… read more here.
Keywords: risk; heart disease; ficolin; rhd ... See more keywords
Low Mannose Binding Lectin, but Not L-Ficolin, Is Associated With Spontaneous Clearance of Hepatitis C Virus After Infection
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2020.587669
Abstract: Some individuals can spontaneously clear the hepatitis C virus (HCV) after infection, whereas others develop a chronic infection. The exact mechanism of this phenomenon is unknown. We aimed to evaluate the association of plasma levels… read more here.
Keywords: infection; clearance; hepatitis virus; virus ... See more keywords
Association of low ficolin-2 concentration in cord serum with respiratory distress syndrome in preterm newborns
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2023.1107063
Abstract: Introduction Ficolin-2 is a serum pattern recognition molecule, involved in complement activation via the lectin pathway. This study aimed to investigate the association of ficolin-2 concentration in cord blood serum with complications related to premature… read more here.
Keywords: cord; serum; concentration; ficolin concentration ... See more keywords