Anti-Ficolin-2 and Anti-Ficolin-3 Autoantibody Detection by ELISA.
Sign Up to like & getrecommendations! Published in 2021 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1016-9_12
Abstract: Ficolins are recognition proteins of the lectin pathway of the complement system and also play an important role in innate immunity and in the maintenance of tissue homeostasis. They deserve special attention in the context… read more here.
Keywords: autoantibody detection; ficolin autoantibody; ficolin anti; detection elisa ... See more keywords
Ficolin-2 triggers antitumor effect by activating macrophages and CD8+ T cells.
Sign Up to like & getrecommendations! Published in 2017 at "Clinical immunology"
DOI: 10.1016/j.clim.2017.08.012
Abstract: Ficolin-2 is an important serum complement lectin. Here, we describe novel findings indicating that serum ficolin-2 concentrations in multiple tumor patients are significantly lower than those in healthy donors. Administration of exogenous ficolin-2 or ficolin-A… read more here.
Keywords: antitumor effect; cells ficolin; ficolin triggers; cd8 cells ... See more keywords
Lectin pathway factors in patients suffering from juvenile idiopathic arthritis
Sign Up to like & getrecommendations! Published in 2017 at "Immunology and Cell Biology"
DOI: 10.1038/icb.2017.31
Abstract: Both complement activation and certain infections (including those with Yersinia sp.) may contribute to the pathogenesis of juvenile idiopathic arthritis (JIA). We investigated factors specific for the lectin pathway of complement: mannose‐binding lectin (MBL), ficolins… read more here.
Keywords: juvenile idiopathic; jia; lectin pathway; idiopathic arthritis ... See more keywords
Ficolin A derived from local macrophages and neutrophils protects against LPS-induced acute lung injury by activating complement.
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DOI: 10.1111/imcb.12344
Abstract: Ficolins are important and widely distributed pattern recognition molecules that can induce lectin complement pathway activation and initiate the innate immune response. Although ficolins can bind lipopolysaccharide (LPS) in vitro, the sources, dynamic changes and roles of local ficolins… read more here.
Keywords: lps induced; injury; lung injury; macrophages neutrophils ... See more keywords
Ficolin‐3 and MASP‐2 gene variants in Siberian arctic populations: Summarized evidence of selective pressure for the high frequency of lectin complement pathway deficiency
Sign Up to like & getrecommendations! Published in 2022 at "Scandinavian Journal of Immunology"
DOI: 10.1111/sji.13249
Abstract: Herewith, we provide novel original data about the prevalence of FCN3 rs532781899 and MASP2 rs72550870 variants among the newborns of aboriginal Siberian Arctic populations (Nenets and Dolgan‐Nganasans) and Russians of East Siberia. This novel data… read more here.
Keywords: lectin complement; prevalence; ficolin; gene ... See more keywords
Low Mannose Binding Lectin, but Not L-Ficolin, Is Associated With Spontaneous Clearance of Hepatitis C Virus After Infection
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DOI: 10.3389/fimmu.2020.587669
Abstract: Some individuals can spontaneously clear the hepatitis C virus (HCV) after infection, whereas others develop a chronic infection. The exact mechanism of this phenomenon is unknown. We aimed to evaluate the association of plasma levels… read more here.
Keywords: infection; clearance; hepatitis virus; virus ... See more keywords
Association of low ficolin-2 concentration in cord serum with respiratory distress syndrome in preterm newborns
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2023.1107063
Abstract: Introduction Ficolin-2 is a serum pattern recognition molecule, involved in complement activation via the lectin pathway. This study aimed to investigate the association of ficolin-2 concentration in cord blood serum with complications related to premature… read more here.
Keywords: cord; serum; concentration; ficolin concentration ... See more keywords