Relationship between Structure and Antibacterial Activity of α-Aminophosphonate Derivatives Obtained via Lipase-Catalyzed Kabachnik−Fields Reaction
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DOI: 10.3390/ma15113846
Abstract: We reported a new method dealing with the synthesis of novel pharmacologically relevant α-aminophosphonate derivatives via a lipase-catalyzed Kabachnik−Fields reaction with yields of up to 93%. The advantages of this protocol are excellent yields, mild… read more here.
Keywords: kabachnik fields; lipase catalyzed; aminophosphonate derivatives; catalyzed kabachnik ... See more keywords
Synthesis of α-Aminophosphonates and Related Derivatives; The Last Decade of the Kabachnik–Fields Reaction
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DOI: 10.3390/molecules26092511
Abstract: The Kabachnik–Fields reaction, comprising the condensation of an amine, oxo compound and a P-reagent (generally a >P(O)H species or trialkyl phosphite), still attracts interest due to the challenging synthetic procedures and the potential biological activity… read more here.
Keywords: kabachnik fields; synthesis aminophosphonates; last decade; fields reaction ... See more keywords