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Published in 2018 at "Journal of the European Academy of Dermatology and Venereology"
DOI: 10.1111/jdv.14532
Abstract: Loss‐of‐function mutations in filaggrin gene (FLG) have been suggested to increase the susceptibility of skin malignancies due to reduced levels of epidermal filaggrin and its degradation products, urocanic acid, which may be protective against ultraviolet…
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Keywords:
loss function;
mutations filaggrin;
function mutations;
filaggrin gene ... See more keywords
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1
Published in 2018 at "Journal of the European Academy of Dermatology and Venereology"
DOI: 10.1111/jdv.14813
Abstract: Filaggrin, a highly abundant protein of the stratum corneum (SC), draw considerable attention after the discovery of its role in the aetiology of atopic dermatitis (AD). Next to its importance for the skin barrier function,…
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Keywords:
filaggrin gene;
study;
tuca;
effect ... See more keywords
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Published in 2021 at "Allergologia et immunopathologia"
DOI: 10.15586/aei.v49i4.209
Abstract: BACKGROUND Filament aggregating protein (Filaggrin) is a skeletal cell component that provides a protective function for the epidermis. Mutations of the filaggrin gene (FLG) cause a loss of filaggrin protein. These mutations are seen in…
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Keywords:
atopic dermatitis;
features children;
filaggrin gene;
clinical features ... See more keywords