Intermediate filaments ensure resiliency of single carcinoma cells, while active contractility of the actin cortex determines their invasive potential
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DOI: 10.1088/1367-2630/ac1899
Abstract: During the epithelial-to-mesenchymal transition, the intracellular cytoskeleton undergoes severe reorganization which allows epithelial cells to transition into a motile mesenchymal phenotype. Among the different cytoskeletal elements, the intermediate filaments keratin (in epithelial cells) and vimentin… read more here.
Keywords: resiliency single; carcinoma; ensure resiliency; intermediate filaments ... See more keywords