Plasma lipoprotein-X quantification on filipin-stained gels: monitoring recombinant LCAT treatment ex vivo.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of lipid research"
DOI: 10.1194/jlr.d090233
Abstract: Familial LCAT deficiency (FLD) patients accumulate lipoprotein-X (LP-X), an abnormal nephrotoxic lipoprotein enriched in free cholesterol (FC). The low neutral lipid content of LP-X limits the ability to detect it after separation by lipoprotein electrophoresis… read more here.
Keywords: electrophoresis; monitoring recombinant; fld; vivo ... See more keywords
The Antifungal Antibiotic Filipin as a Diagnostic Tool of Cholesterol Alterations in Lysosomal Storage Diseases and Neurodegenerative Disorders
Sign Up to like & getrecommendations! Published in 2023 at "Antibiotics"
DOI: 10.3390/antibiotics12010122
Abstract: Cholesterol is the most considerable member of a family of polycyclic compounds understood as sterols, and represents an amphipathic molecule, such as phospholipids, with the polar hydroxyl group located in position 3 and the rest… read more here.
Keywords: diagnostic tool; tool cholesterol; storage diseases; cholesterol ... See more keywords