Filopodia Quantification Using FiloQuant.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-9686-5_16
Abstract: Filopodia are fingerlike membrane protrusions that are extended by cells in vitro and in vivo. Due to important roles in sensing the extracellular microenvironment, filopodia and filopodia-like protrusions have been implicated in numerous biological processes… read more here.
Keywords: filopodia like; filopodia; filopodia quantification; filopodia filopodia ... See more keywords
Filopodome Mapping Identifies p130Cas as a Mechanosensitive Regulator of Filopodia Stability
Sign Up to like & getrecommendations! Published in 2019 at "Current Biology"
DOI: 10.1016/j.cub.2018.11.053
Abstract: Summary Filopodia are adhesive cellular protrusions specialized in the detection of extracellular matrix (ECM)-derived cues. Although ECM engagement at focal adhesions is known to trigger the recruitment of hundreds of proteins (“adhesome”) to fine-tune cellular… read more here.
Keywords: mapping; filopodia stability; filopodia; regulator filopodia ... See more keywords
Fluorescent Artificial Antigens Revealed Extended Filopodia Networks Utilized by Live Dendritic Cells for Antigen Uptake.
Sign Up to like & getrecommendations! Published in 2022 at "Nano letters"
DOI: 10.1021/acs.nanolett.2c00629
Abstract: Dendritic cells (DCs) can infiltrate tight junctions of the epithelium to collect remote antigens during immune surveillance. While membrane filopodia represent a plausible structure to perform this task, their functional mechanisms remain elusive owing to… read more here.
Keywords: antigens revealed; filopodia; artificial antigens; dendritic cells ... See more keywords
Intraflagellar transport proteins are involved in thrombocyte filopodia formation and secretion
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DOI: 10.1080/09537104.2017.1361524
Abstract: Abstract Intraflagellar transport (IFT) proteins are vital for the genesis and maintenance of cilia. Our identification of ift122 transcripts in zebrafish thrombocytes that lack primary cilia was unexpected. IFT proteins serve transport in cilia, whose… read more here.
Keywords: secretion; proteins involved; filopodia; intraflagellar transport ... See more keywords
Induced Arp2/3 Complex Depletion Increases FMNL2/3 Formin Expression and Filopodia Formation
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2021.634708
Abstract: The Arp2/3 complex generates branched actin filament networks operating in cell edge protrusion and vesicle trafficking. Here we employ a conditional knockout mouse model permitting tissue- or cell-type specific deletion of the murine Actr3 gene… read more here.
Keywords: arp2 complex; filopodia; formin expression; formation ... See more keywords
Dynamics of Endothelial Engagement and Filopodia Formation in Complex 3D Microscaffolds
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23052415
Abstract: The understanding of endothelium–extracellular matrix interactions during the initiation of new blood vessels is of great medical importance; however, the mechanobiological principles governing endothelial protrusive behaviours in 3D microtopographies remain imperfectly understood. In blood capillaries… read more here.
Keywords: filopodia formation; engagement filopodia; filopodia; endothelial engagement ... See more keywords