PRR11 induces filopodia formation and promotes cell motility via recruiting ARP2/3 complex in non-small cell lung cancer cells
Sign Up to like & getrecommendations! Published in 2021 at "Genes and Diseases"
DOI: 10.1016/j.gendis.2021.02.012
Abstract: Abstract Filopodia, a finger-like structure and actin-rich plasma-membrane protrusion at the leading edge of the cell, has important roles in cell motility. However, the mechanisms of filopodia generation are not well-understood via the actin-related protein… read more here.
Keywords: arp2 complex; cell; filopodia formation; cell motility ... See more keywords
Spatiotemporal Regulation of FMNL2 by N-Terminal Myristoylation and C-Terminal Phosphorylation Drives Rapid Filopodia Formation
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DOI: 10.3390/biom13030548
Abstract: The actin nucleating and polymerizing formin-like 2 (FMNL2) is upregulated in several cancers and has been shown to play important roles in cell migration, invasion, cell–cell adhesion and filopodia formation. Here, using structured illumination microscopy… read more here.
Keywords: filopodia formation; terminal myristoylation; spatiotemporal regulation; formation ... See more keywords
Dynamics of Endothelial Engagement and Filopodia Formation in Complex 3D Microscaffolds
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DOI: 10.3390/ijms23052415
Abstract: The understanding of endothelium–extracellular matrix interactions during the initiation of new blood vessels is of great medical importance; however, the mechanobiological principles governing endothelial protrusive behaviours in 3D microtopographies remain imperfectly understood. In blood capillaries… read more here.
Keywords: filopodia formation; engagement filopodia; filopodia; endothelial engagement ... See more keywords