Measurement of Chaperone-Mediated Effects on Polyglutamine Protein Aggregation by the Filter Trap Assay.
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DOI: 10.1007/978-1-4939-7477-1_5
Abstract: The formation of aggregates by polyglutamine-containing (polyQ) proteins in neurons is a key to the pathogenesis of several progressive neurodegenerative diseases such as Huntington's disease (HD) spinocerebellar ataxias (SCAs), and spinal and bulbar muscular atrophy… read more here.
Keywords: trap assay; filter trap; chaperone; polyq ... See more keywords