Filtering cells with high mitochondrial content depletes viable metabolically altered malignant cell populations in cancer single-cell studies
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DOI: 10.1186/s13059-025-03559-w
Abstract: Single-cell transcriptomics has transformed our understanding of cellular diversity, yet noise from technical artifacts and low-quality cells can obscure key biological signals. A common practice is filtering out cells with a high percentage of mitochondrial… read more here.
Keywords: cancer; cells high; single cell; filtering cells ... See more keywords