Nanoemulgel for Efficient Topical Delivery of Finasteride Against Androgenic Alopecia
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Pharmaceutical Innovation"
DOI: 10.1007/s12247-020-09483-9
Abstract: This investigation was aimed to develop and evaluate lipid nanoemulsion-based gel of finasteride for topical administration, to increase drug availability into the skin for a long duration and to improve the in vivo potential of… read more here.
Keywords: nanoemulgel efficient; alopecia; skin; finasteride ... See more keywords
Anti-androgenic therapy with finasteride in patients with chronic heart failure - a retrospective propensity score based analysis
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-46640-8
Abstract: Sex hormones influence the prevalence and the outcome of heart diseases. The conversion of testosterone to its more active metabolite dihydrotestosterone drives cardiac growth and dysfunction, while inhibition of this step by the anti-androgenic drug… read more here.
Keywords: heart; analysis; finasteride; heart failure ... See more keywords
In vivo and in silico evaluation of the ameliorative effect of hesperidin on finasteride-induced testicular oxidative stress in Wistar rats
Sign Up to like & getrecommendations! Published in 2020 at "Toxicology Mechanisms and Methods"
DOI: 10.1080/15376516.2020.1831123
Abstract: Abstract Finasteride used for treating benign prostatic hyperplasia is associated with undesirable side effects via oxidative stress related mechanisms. This study employed in vivo and in silico methods to investigate the protective role of hesperidin… read more here.
Keywords: vivo silico; finasteride; hesperidin; wistar rats ... See more keywords
Topical finasteride for male and female pattern hair loss: Is it a safe and effective alternative?
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cosmetic Dermatology"
DOI: 10.1111/jocd.14895
Abstract: Oral finasteride is an FDA‐approved treatment for androgenetic alopecia (AGA). Topical finasteride, while not FDA‐approved, lacks the systemic adverse effects associated with oral finasteride. The efficacy of topical finasteride has been evaluated. read more here.
Keywords: finasteride male; pattern hair; male female; topical finasteride ... See more keywords
The effect of 3-month finasteride challenge on biomarkers for predicting cancer outcome on biopsy: Results of a randomized trial
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DOI: 10.1371/journal.pone.0204823
Abstract: Background Finasteride, a 5-alpha reductase inhibitor may have effects on biomarkers such as prostate-specific antigen (PSA) that could be leveraged to improve screening. Objective To determine the predictive characteristics of biomarkers for prostate cancer for… read more here.
Keywords: biopsy; finasteride; prostate cancer; cancer ... See more keywords
Altered methylation pattern of the SRD5A2 gene in the cerebrospinal fluid of post-finasteride patients: a pilot study
Sign Up to like & getrecommendations! Published in 2019 at "Endocrine Connections"
DOI: 10.1530/ec-19-0199
Abstract: Context Post-finasteride syndrome (PFS) occurs in patients with androgenic alopecia after suspension of the finasteride treatment, leading to a large variety of persistent side effects. Despite the severity of the clinical picture, the mechanism underlying… read more here.
Keywords: methylation; finasteride; methylation pattern; pfs patients ... See more keywords
Protective effect of DA-9401 in finasteride-induced apoptosis in rat testis: inositol requiring kinase 1 and c-Jun N-terminal kinase pathway
Sign Up to like & getrecommendations! Published in 2017 at "Drug Design, Development and Therapy"
DOI: 10.2147/dddt.s140543
Abstract: Finasteride is used to treat male pattern baldness and benign prostatic hyperplasia. This study investigated the toxicity of finasteride and recovery by DA-9401 using Sprague Dawley (SD) rats. Forty adult male SD rats were assigned… read more here.
Keywords: testis; apoptosis; protective effect; kinase ... See more keywords