Identification and fine mapping of a major locus controlling branching in Brassica napus
Sign Up to like & getrecommendations! Published in 2019 at "Theoretical and Applied Genetics"
DOI: 10.1007/s00122-019-03506-x
Abstract: A candidate branching-controlling gene for qDBA09 was identified after delimiting a Brassica napus recessive locus within a 270-kb interval on chromosome A09. Although branching is an important trait associated with the adaptation and yield potential… read more here.
Keywords: brassica; fine mapping; analysis; brassica napus ... See more keywords
Fine mapping QSc.VR4, an effective and stable scald resistance locus in barley (Hordeum vulgare L.), to a 0.38-Mb region enriched with LRR-RLK and GLP genes
Sign Up to like & getrecommendations! Published in 2020 at "Theoretical and Applied Genetics"
DOI: 10.1007/s00122-020-03599-9
Abstract: An effective and stable quantitative resistance locus, QSc.VR4, was fine mapped, characterized and physically anchored to the short arm of 4H, conferring adult plant resistance to the fungus Rhynchosporium commune in barley. Scald caused by… read more here.
Keywords: barley; effective stable; resistance; qsc vr4 ... See more keywords
Characterization and fine mapping of qPE12, a new locus controlling rice panicle exsertion
Sign Up to like & getrecommendations! Published in 2017 at "Euphytica"
DOI: 10.1007/s10681-017-2104-0
Abstract: Panicle exsertion is an important agronomic trait involved in pollination and hybrid rice seed production. The identification of genes controlling panicle exsertion will play a central role in hybrid rice breeding. C115, a chromosome segment… read more here.
Keywords: panicle exsertion; fine mapping; rice; panicle ... See more keywords
Fine mapping, candidate genes analysis, and characterization of a brown planthopper (Nilaparvata lugens Stål) resistance gene in the rice variety ARC5984
Sign Up to like & getrecommendations! Published in 2019 at "Euphytica"
DOI: 10.1007/s10681-019-2546-7
Abstract: The brown planthopper (Nilaparvata lugens Stål; BPH) is the most destructive rice pests worldwide. Identification and application of major resistance genes and cultivation of resistant varieties are the most efficient methods to control this insect.… read more here.
Keywords: rice; resistance gene; resistance; candidate genes ... See more keywords
Allele-Specific QTL Fine Mapping with PLASMA.
Sign Up to like & getrecommendations! Published in 2020 at "American journal of human genetics"
DOI: 10.1016/j.ajhg.2019.12.011
Abstract: Although quantitative trait locus (QTL) associations have been identified for many molecular traits such as gene expression, it remains challenging to distinguish the causal nucleotide from nearby variants. In addition to traditional QTLs by association,… read more here.
Keywords: causal variants; qtl based; mapping; allele specific ... See more keywords
Fine mapping of a novel male-sterile mutant showing wrinkled-leaf in sesame by BSA-Seq technology
Sign Up to like & getrecommendations! Published in 2020 at "Industrial Crops and Products"
DOI: 10.1016/j.indcrop.2020.112862
Abstract: Abstract Genic male sterility (GMS) is a very important approach of heterosis exploitation in sesame (Sesamum indicum L.). Visible marker-trait linked to GMS is necessary since it can facilitate the breeding of new GMS lines… read more here.
Keywords: sesame; wrinkled leaf; showing wrinkled; male ... See more keywords
The flashfm approach for fine-mapping multiple quantitative traits.
Sign Up to like & getrecommendations! Published in 2021 at "Nature communications"
DOI: 10.1038/s41467-021-26364-y
Abstract: Joint fine-mapping that leverages information between quantitative traits could improve accuracy and resolution over single-trait fine-mapping. Using summary statistics, flashfm (flexible and shared information fine-mapping) fine-maps signals for multiple traits, allowing for missing trait measurements… read more here.
Keywords: causal variants; mapping; single trait; fine mapping ... See more keywords
Genome-wide meta-analysis, fine-mapping, and integrative prioritization implicate new Alzheimer’s disease risk genes
Sign Up to like & getrecommendations! Published in 2021 at "Nature genetics"
DOI: 10.1038/s41588-020-00776-w
Abstract: Genome-wide association studies (GWAS) have discovered numerous genomic loci associated with Alzheimer’s disease (AD), yet the causal genes and variants remain incompletely identified. We performed an updated genome-wide AD meta-analysis, which identified 37 risk loci,… read more here.
Keywords: genome wide; risk; alzheimer disease; wide meta ... See more keywords
Multi-ancestry fine mapping implicates OAS1 splicing in risk of severe COVID-19
Sign Up to like & getrecommendations! Published in 2022 at "Nature Genetics"
DOI: 10.1038/s41588-021-00996-8
Abstract: The OAS1/2/3 cluster has been identified as a risk locus for severe COVID-19 among individuals of European ancestry, with a protective haplotype of approximately 75 kilobases (kb) derived from Neanderthals in the chromosomal region 12q24.13.… read more here.
Keywords: risk; ancestry; fine mapping; ancestry fine ... See more keywords
Genetic associations at regulatory phenotypes improve fine-mapping of causal variants for 12 immune-mediated diseases.
Sign Up to like & getrecommendations! Published in 2022 at "Nature genetics"
DOI: 10.1038/s41588-022-01025-y
Abstract: The resolution of causal genetic variants informs understanding of disease biology. We used regulatory quantitative trait loci (QTLs) from the BLUEPRINT, GTEx and eQTLGen projects to fine-map putative causal variants for 12 immune-mediated diseases. We… read more here.
Keywords: causal variants; fine mapping; variants immune; disease ... See more keywords
Fine-mapping sequence mutations with a major effect on oligosaccharide content in bovine milk
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-38488-9
Abstract: Human milk contains abundant oligosaccharides (OS) which are believed to have strong health benefits for neonates. OS are a minor component of bovine milk and little is known about how the production of OS is… read more here.
Keywords: milk; bovine milk; sequence mutations; mapping sequence ... See more keywords