Overt Hypogonadism May Not Be a Sentinel Sign of RING Finger Protein 216: Two Novel Mutations Associated with Ataxia, Chorea, and Fertility
Sign Up to like & getrecommendations! Published in 2019 at "Movement Disorders Clinical Practice"
DOI: 10.1002/mdc3.12839
Abstract: We describe a fertile patient presenting a Huntington-like disorder, normal peripheral nerve conduction, and atypical magnetic resonance imaging (MRI) findings who harbored 2 novel mutations in RING Finger Protein 216 (RNF216). A 44-year-old woman developed… read more here.
Keywords: protein 216; associated ataxia; novel mutations; ring finger ... See more keywords
The microtubule-associated RING finger protein 1 (OsMAR1) acts as a negative regulator for salt-stress response through the regulation of OCPI2 (O. sativa chymotrypsin protease inhibitor 2)
Sign Up to like & getrecommendations! Published in 2017 at "Planta"
DOI: 10.1007/s00425-017-2834-1
Abstract: Main conclusionOur results suggest that a rice E3 ligase, OsMAR1, physically interacts with a cytosolic protein OCPI2 and may play an important role under salinity stress.Salt is an important abiotic stressor that negatively affects plant… read more here.
Keywords: protein; associated ring; response; microtubule associated ... See more keywords
Aberrant Active cis-Regulatory Elements Associated with Downregulation of RET Finger Protein Overcome Chemoresistance in Glioblastoma.
Sign Up to like & getrecommendations! Published in 2019 at "Cell reports"
DOI: 10.1016/j.celrep.2019.01.109
Abstract: RET finger protein (RFP) forms a complex with histone deacetylase 1, resulting in aberrant deacetylation of H3K27ac and dysregulation of cis-regulatory elements. We evaluated the modulatory effects of RFP knockdown on cis-regulatory elements, gene expression,… read more here.
Keywords: glioblastoma; ret finger; cis regulatory; finger protein ... See more keywords
Really interesting new gene finger protein 121 is a tumor suppressor of renal cell carcinoma.
Sign Up to like & getrecommendations! Published in 2018 at "Gene"
DOI: 10.1016/j.gene.2018.08.067
Abstract: Really interesting new gene finger protein (RING) finger protein 121 (RNF-121) is an E3 ubiquitin ligase involved in the regulation of several signaling pathways. Among those signaling pathways, nuclear factor-κB (NF-κB) signaling pathway is known… read more here.
Keywords: rcc; really interesting; finger protein; gene ... See more keywords
A C2H2 zinc-finger protein OsZFP213 interacts with OsMAPK3 to enhance salt tolerance in rice.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of plant physiology"
DOI: 10.1016/j.jplph.2018.07.003
Abstract: Improvement of salt tolerance is one of the major targets in rice breeding. Here, we report that the zinc-finger protein (ZFP) OsZFP213 functions in enhancing salt tolerance in rice. OsZFP213 is localized in the nucleus… read more here.
Keywords: rice; tolerance; zinc finger; salt tolerance ... See more keywords
Discovery of an H3K36me3-Derived Peptidomimetic Ligand with Enhanced Affinity for Plant Homeodomain Finger Protein 1 (PHF1).
Sign Up to like & getrecommendations! Published in 2021 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.1c00430
Abstract: Plant homeodomain finger protein 1 (PHF1) is an accessory component of the gene silencing complex polycomb repressive complex 2 and recognizes the active chromatin mark, trimethylated lysine 36 of histone H3 (H3K36me3). In addition to… read more here.
Keywords: plant homeodomain; protein phf1; homeodomain finger; finger protein ... See more keywords
LEAFY and APETALA1 down-regulate ZINC FINGER PROTEIN 1 and 8 to release their repression on class B and C floral homeotic genes
Sign Up to like & getrecommendations! Published in 2023 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2221181120
Abstract: Significance Proper repression of the floral homeotic genes AP3, PI, and AG in leaf primordia and activation of them in floral meristems is essential for reproductive fitness. Many studies have revealed molecular details about the… read more here.
Keywords: finger protein; homeotic genes; repression; floral meristems ... See more keywords
Overexpression of zinc-finger protein 677 inhibits proliferation and invasion by and induces apoptosis in clear cell renal cell carcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Bioengineered"
DOI: 10.1080/21655979.2022.2038891
Abstract: ABSTRACT Recent studies have demonstrated that zinc-finger protein 677 (ZNF677) acts as a tumor suppressor gene in cancer. However, the expression and function of ZNF677 in clear cell renal cell carcinoma (ccRCC) are still unclear.… read more here.
Keywords: cell; znf677; finger protein; ccrcc ... See more keywords
Plant homeodomain finger protein 6 in the regulation of normal and malignant hematopoiesis.
Sign Up to like & getrecommendations! Published in 2020 at "Current Opinion in Hematology"
DOI: 10.1097/moh.0000000000000588
Abstract: PURPOSE OF REVIEW Even though an increasing amount of sequencing data on the leukemia genome has highlighted a tumor-suppressive function for plant homeodomain finger protein 6 (PHF6), its role in the hematopoietic system remained elusive… read more here.
Keywords: phf6; homeodomain finger; plant homeodomain; finger protein ... See more keywords
Association between the zinc finger protein 804A (ZNF804A) gene and the risk of schizophrenia and bipolar I disorder across diagnostic boundaries
Sign Up to like & getrecommendations! Published in 2017 at "Bipolar Disorders"
DOI: 10.1111/bdi.12493
Abstract: In this study, we aimed to determine the role of genetic variations within the zinc finger protein 804A (ZNF804A) gene, a candidate for a psychosis risk‐conferring gene, in the development of schizophrenia (SZ) and bipolar… read more here.
Keywords: zinc finger; protein 804a; znf804a gene; finger protein ... See more keywords
Ring finger protein 19A is overexpressed in non‐small cell lung cancer and mediates p53 ubiquitin‐degradation to promote cancer growth
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.16674
Abstract: The expression pattern, biological functions and the related mechanisms of the ring finger protein 19A (RNF19A) in non‐small cell lung cancer (NSCLC) remain poorly understood. This study aimed to explore the role of RNF19A, as… read more here.
Keywords: ring finger; rnf19a; finger protein; cancer ... See more keywords